Wrinkles Clinical Trial
Official title:
Pilot Study on the Effects of Oral Triphala and Rubia Cordifolia on the Gut Microbiome and Skin Biophysical Properties
Few studies have assessed the effects of Triphala and Rubia Cordifolia from a skin biophysical perspective. Here, we aim to understand how these herbs can modulate the skin's barrier properties and the gut microbiome.
Herbal supplements such as Rubia cordifolia and Triphala [a mix of Emblica officinalis
(Amalaki), Terminalia bellerica (Bibhitaki), and Terminalia chebula (Haritaki)] are commonly
used for skin based treatments in India. However, the scientific evidence for their specific
effects on the skin are scant. Rubia cordifolia is a root that is used in skin care for
pigmentation and inflammation.1 Triphala is thought to have antioxidant properties and reduce
inflammation in general. Herbs have been shown to modulate the gut microbiome, as previous
studies have suggested that triphala may modify the gut microbiome.2
However, few studies have assessed the effects of these herbs from a skin biophysical
perspective. Here, we aim to understand how these herbs can modulate the skin's barrier
properties and the gut microbiome.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT01984619 -
Prospective Study Evaluating the Treatment of Hyperdynamic Forehead Wrinkles
|
N/A | |
Completed |
NCT01713985 -
Feasibility Study: Evaluation of Ulthera Versus Thermage for Treating the Face and Neck
|
N/A | |
Recruiting |
NCT01586819 -
Lateral Canthal Rhytides With Medium Depth Chemical Peel With or Without Pretreatment With Botulinum Toxin A
|
Phase 3 | |
Completed |
NCT05254210 -
Feasibility Study To Collect Safety And Preliminary Efficacy Data For A Radiofrequency Microneedling Device
|
N/A | |
Completed |
NCT02604641 -
Assessment of the Impact of a Coenzyme Q10 Supplementation on the Skin
|
N/A | |
Completed |
NCT01519934 -
A Retrospective Study to Evaluate the Effectiveness of the Ulthera System
|
N/A | |
Completed |
NCT01460927 -
TriActive+ Radiofrequency (RF) for Non-invasive Treatment of Wrinkles & Rhytides
|
N/A | |
Completed |
NCT03811756 -
The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin Parameters
|
N/A | |
Completed |
NCT04988412 -
The Effect of 12-week Dietary Intake of Food Supplements Containing Collagen on Dermis Density and Other Skin Parameters
|
N/A | |
Completed |
NCT02913547 -
Silk'n HST for Wrinkle Reduction - Clinical Study Protocol
|
N/A | |
Active, not recruiting |
NCT02019004 -
A Pilot Study Testing Onabotulinum Toxin A Versus Incobotulinum Toxin A Injections for Facial Wrinkles
|
N/A | |
Completed |
NCT02340078 -
A Clinical Study to Evaluate the Efficacy and Safety of YVOIRE Volume Plus Versus YVOIRE Volume in Nasolabial Fold Injection
|
N/A | |
Completed |
NCT01283464 -
Comparison of Retinol 1.0% and Tretinoin 0.02% in the Treatment of Moderate to Severe Photodamage and Wrinkles
|
Phase 2 | |
Completed |
NCT01034956 -
Outcomes and Patient Experience After Soft Tissue Dermal Filler Injections
|
N/A | |
Completed |
NCT02425943 -
Sculptra Aesthetic Post-Approval Study
|
Phase 4 | |
Recruiting |
NCT05847530 -
Pilot Evaluation of the Cynosure Potenza™ System for Treatment of Cosmetic Dermatologic Skin Conditions
|
N/A | |
Enrolling by invitation |
NCT01847066 -
Epidermal Delivery of Ani-Aging Ingredients
|
N/A | |
Completed |
NCT01859611 -
TriActive+ Radiofrequency (RF) for Non-Invasive Treatment of Wrinkles and Rhytides
|
N/A | |
Completed |
NCT01297634 -
Radial Diffusion of the Botulinum Toxin Type A (Botox®): Electromyographic Evaluation of the Frontal Muscle
|
Phase 4 | |
Completed |
NCT05011461 -
The Effect of Topical Almond Oil vs. Topical Retinol on The Appearance of Facial Wrinkles
|
N/A |