Clinical Trials Logo
  1. Home
  2. Erythema
  3. NCT02832141
  4. Details
NCT02832141 Clinical Trial

Effect of Thoracic Spine Mobilization on Sympathetic Nervous Systems

Erythema Clinical Trial

Official title:
Effect of Thoracic Spine Mobilization on Skin-blood Flow, Erythema and Sympathetic Nervous Systems

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02832141
Other study ID # Mobilization Thoracic Spine
Secondary ID
Status Completed
Phase
First received
Last updated
Start date May 2016
Est. completion date December 31, 2018

Study information
Verified date January 2019
Source Bern University of Applied Sciences
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This pilot study aims to i) represents the feasibility of the study design and ii) to point out acute effects of thoracic spine mobilization on skin-blood flow, erythema and the sympathetic nervous system.

Recruitment information / eligibility
Status Completed
Enrollment 14
Est. completion date December 31, 2018
Est. primary completion date December 31, 2018
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 20 Years to 30 Years
Eligibility Inclusion Criteria:

- age 20 - 30 years

- healthy persons

Exclusion Criteria:

- current pain

- blood pressure medications

- osteoporosis

- cardiac or neurological symptoms

- pregnancy

- thromobosis

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Mobilization anterior
Participant in prone position. Central thoracic mobilization from posterior-to-anterior.
• Mobilization posterior
Participant in sitting position. Central thoracic mobilization from anteriors-to-posterior.

Locations
Country Name City State
Switzerland Bern University of Applied Science, Department Health Bern

Sponsors (1)
Lead Sponsor Collaborator
Bern University of Applied Sciences

Country where clinical trial is conducted

Switzerland, 

Outcome
Type Measure Description Time frame Safety issue
Primary Feasibility: Adherence of recruited participants Defined as the number of drop-outs and presence of participants which invited. Measurement unit: number Every 4 weeks up to 2 years
Primary Feasibility of the investigating procedure Measured the burden of testing procedure. Measurement units = number and percentage Every 4 weeks up to 2 years
Primary Feasibility of the mobilization intervention from posterior-to-anterior on thoracic vertebrae Measured adverse effects as pain and harm results to participants. Measurement units = number and percentage Every 4 weeks up to 2 years
Primary Feasibility of the mobilization intervention from anterior-to-posterior on thoracic vertebrae Measured as adverse effects as pain and harm results to participants. Measurement units = number and percentage. Every 4 weeks up to 2 years
Secondary Rate of heart rate variability (HRV) HRV is measured as the variations of the time interval between two consecutive cardiac beats registered by means Polar watch RS800 is used to measures (HRV). Measurement unit: High frequency-band (HF-Band) and Low frequency-band (LF-Band) Change from baseline imediately after, 2, 4, 6, 8 and 10 minutes after the intervention
Secondary Rate of systolic blood pressure value (mmHg) Omron MIT Elite Plus is used for measuring systolic blood flow. iMeasurement units: mmHg (millimeter of mercury) Change from baseline imediately after, 2, 4, 6, 8 and 10 minutes after the intervention
Secondary Rate of diastolic blood pressure value (mmHg) changes Omron MIT Elite Plus is used for measuring diastolic blood pressureMeasurement units: mmHg (millimeter of mercury) Change from baseline imediately after, 2, 4, 6, 8 and 10 minutes after the intervention
Secondary Rate of heartbeat frequency Polar watch RS800 is used for measuring heartbeat frequency. Measurement units: beat per minute (bpm) Change from baseline imediately after, 2, 4, 6, 8 and 10 minutes after the intervention
Secondary Rate of skin-blood flow variation Laser doppler imaging is used for measuring microcirculatory changes. Measurement units: perfusion unit Change from baseline imediately after, 2, 4, 6, 8 and 10 minutes after the intervention
Secondary Rate of erythema Tristimulus surface colorimetry is used for measuring erythema. Measurement units: Erythema index Change from baseline imediately after, 2, 4, 6, 8 and 10 minutes after the intervention
See also
  Status Clinical Trial Phase
Withdrawn NCT04290273 - Characterisation of the Time-course Response of UV-induced Erythema N/A
Completed NCT01659853 - Efficacy and Safety Study Comparing CD07805/47 Gel 0.5% to Azelaic Acid Gel 15% in Subjects With Erythema of Rosacea Phase 3
Completed NCT00839462 - Efficacy of Dexpanthenol in Thermic Erythema Phase 2
Not yet recruiting NCT06016361 - Evaluation of a Novel Amino Acid Based Moisturizing Cream as Part of the Daily Standard Skincare Regimen Recommended During Radiation Therapy N/A
Completed NCT03633877 - Durapore vs. Hy-Tape to Secure The Endotracheal Tube N/A
Active, not recruiting NCT02876107 - Carboplatin and Paclitaxel With or Without Panitumumab in Treating Patients With Invasive Triple Negative Breast Cancer Phase 2
Completed NCT06369675 - Skin Irritation Potential of MOB015B in Healthy Subjects Using a Cumulative Irritant Patch Test Design Phase 1
Completed NCT03352323 - An Evaluation of the Reduction in Erythema in Adult Patients With Moderate to Severe Persistent Facial Erythema Associated With Rosacea Phase 3
Completed NCT06369727 - Study to Evaluate the Sensitizing Potential of MOB015B in Healthy Subjects Using a Repeat Insult Patch Test Design Phase 1
Completed NCT03041064 - Multiday Beach Study N/A
Completed NCT02131636 - Efficacy and Safety of AGN-199201 in Patients With Persistent Erythema Associated With Rosacea Phase 3
Terminated NCT01597921 - A DB Randomized Study of R1 and R2 WaterJel / AloeVera Jell in Prevention of Radiation Dermatitis in Breast Cancer N/A
Completed NCT01636765 - Study of Inter- and Intra-rater Reliability of the Clinician Erythema Assessment Scale
Completed NCT01124513 - Melanin Index in Those With Fitzpatrick Skin Phototypes I-VI N/A
Terminated NCT03496584 - Effects of Phytonutrients on Vascular Health and Skin in Obese Males N/A
Completed NCT02737592 - A Clinical Study to Evaluate the Safety of a Personal Lubricant in Healthy Female Subjects N/A
Completed NCT03852563 - A Study to Gain Information How Well Dexpanthenol Derma Cream Helps the Face Skin to Recover After Cosmetic Lasering N/A
Completed NCT05300542 - Efficacy Study of a Novel Skin Health Product to Reduce an UVB Induced Erythema N/A
Completed NCT03477825 - Pilot Study of Triphala and Rubia Cordifolia on Gut Microbiome and Skin N/A
Completed NCT02490943 - A Pilot Study of Warm and Cold Compress to Reduce Injection Site Erythema Due to Peginterferon-beta-1a in MS N/A