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Erosive Reflux Disease clinical trials

View clinical trials related to Erosive Reflux Disease.

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NCT ID: NCT05267743 Completed - Clinical trials for Erosive Reflux Disease

Study to Confirm the Safety and Efficacy of Tegoprazan in Patients With Healed Erosive Reflux Disease

Start date: February 16, 2021
Phase: Phase 4
Study type: Interventional

This study is designed to evaluate the efficacy and safety of Tegoprazan 50mg, compared to Lansoprazole 30mg in patients with healed erosive reflux disease confirmed by endoscopy following oral administration once daily(QD) of 2 weeks or 4 weeks.

NCT ID: NCT04309916 Completed - Clinical trials for Erosive Reflux Disease

Study to Evaluate the Efficacy and Safety of Tegoprazan in ERD Patients With Nighttime Heartburn and Sleep Disturbance

Start date: May 22, 2020
Phase: Phase 4
Study type: Interventional

This study aims to compare the nighttime heartburn and sleep disturbance improvement effect of Tegoprazan 50mg and Eomeprazole 40mg in patients with ERD patients.

NCT ID: NCT01797939 Completed - Clinical trials for Non-erosive Reflux Disease

Predictors of Proton Pump Inhibitor Response in Gastroesophageal Reflux Disease Patients

Start date: July 2008
Phase: N/A
Study type: Observational

Proton pump inhibitor (PPI) is widely used in patients with gastroesophageal reflux disease (GERD), however, some patients fail to respond to PPI therapy. Recent reporters suggest that depressive disorders, anxiety, sleep dysfunction were related with the symptomatic responses to a PPI treatments. Nevertheless, the predictive factors of response to PPI treatment still remain controversial. Therefore, the aims of this study were to investigate the efficacy of PPI therapy, and to evaluate the predictors of the PPI response in patients with symptomatic GERD by using the questionnaire which consisted of GERD symptoms, GERD impact scale (GIS), Epworth sleepiness scale (ESS), Pittsburgh sleep quality index (PSQI), Hospital anxiety and depression scale (HADS), and WHO quality of life scale abbreviated version (WHOQOL-BREF).