Erectile Dysfunction Clinical Trial
Official title:
Preservation of Penile Tumescence by Cavernous Tissue Preservation During Penile Prosthesis Implantation
Spontaneous penile tumescence after penile prosthesis implantation has been previously reported as sporadically occurring during implant surgery. This study aims at systematically preserving residual erectile function, by the preservation of the patients' spontaneous penile tumescence by systematically sparing cavernous tissue during penile prosthesis implantation.
Patients undergoing the cavernous tissue sparing penile implant procedure will be injected
intraoperatively with 40µg alprostadil, a prostaglandin E1 agonist intracorporal injection
(ICI). The procedure will begin as soon as maximal tumescence is attained.
In the cavernous sparing group, corporal dilation will be done solely with a size 8 dilator.
The insertion of the dilator will be carefully inserted in what we call the path of least
resistance. To determine the path of least resistance, the corporotomy is spread apart by
pulling on previously set stay sutures. The path of least resistance is the plane with
maximum outflow of blood from the intraoperatively pharmaceutically dilated and blood filled
corpora cavernosa. This plane can also be anticipated with a preoperative penile duplex.
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