Epithelioid Hemangioma of Bone And Soft Tissue

Epithelioid Hemangioma Clinical Trial

— EE-META  

Official title:

Epithelioid Hemangioma of Bone And Soft Tissue: a Benign Tumor With Metastatic Potential

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03169595
• Other study ID #: 0033566
• Status: Completed
• Phase: N/A
• First received: May 17, 2017
• Last updated: May 26, 2017
• Start date: October 7, 2015
• Est. completion date: May 17, 2017

Study information

• Verified date: May 2017
• Source: Istituto Ortopedico Rizzoli
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The controversy surrounding epithelioid hemangioma diagnosis stems from its somewhat aggressive clinical characteristics, including multifocal presentation and occasional lymph node involvement.

The investigators reviewed the clinicopathologic and radiologic characteristics of bone and soft tissue epithelioid hemangioma in patients treated at our institution with available tissue for molecular testing.

The hypothesis is that epithelioid hemangioma may present with multifocal involvement and rare loco-regional lymph node metastasis, but it remains a benign tumor with excellent prognosis.

Description:

The investigators retrospectively reviewed patients treated for epithelioid hemangioma of the bone and soft tissue in a single insitution. The purpose of this study is to evaluate the pathological, clinical, and radiological characteristics of epithelioid hemangioma arising within bone and soft tissue, in the first cohort of cases where the definitive diagnosis is supplemented by molecular techniques.

The hypothesis is that the improved knowledge regarding this rare entity can more definitively elucidate the benign biology of epithelioid hemangioma.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 70
• Est. completion date: May 17, 2017
• Est. primary completion date: May 17, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• patients with epithelioid hemangioma of bone and soft tissue in the extremities and pelvis

Exclusion Criteria:

• patients with epithelioid hemangioma of bone and soft tissue in the spine

Related Conditions & MeSH terms

• Epithelioid Hemangioma
• Epithelioid Hemangioma of Bone
• Hemangioma

Intervention

Procedure:
• Surgery
Patients affected by epithelioid hemangioma treated with surgery

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Istituto Ortopedico Rizzoli

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Multifocal presentation of patients with epithelioid hemangioma of bone and soft tissue without producing a fatal outcome	The investigators defined multifocal presentation the presence of secondary lesions by imaging at presentation of the disease or during follow-up.	2 years