Epipericardial Fat Necrosis: A Misdiagnosed Condition

Epipericardial Fat Necrosis Clinical Trial

— epipericardial  

Official title:

Epipericardial Fat Necrosis: A Misdiagnosed Condition

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01903980
• Other study ID #: Epipericardial Fat Necrosis
• Secondary ID: Pericardial Necr
• Status: Completed
• Phase: N/A
• First received: July 17, 2013
• Last updated: July 17, 2013
• Start date: June 2013
• Est. completion date: July 2013

Study information

• Verified date: July 2013
• Source: Hospital Sirio-Libanes
• Contact: n/a
• Is FDA regulated: No
• Health authority: Brazil: Brazilian Research Ethics National Commitee
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Epipericardial fat necrosis is a benign and self-limited condition that mainly curses with acute pleuritic chest pain and therefore must be an important differential diagnosis for patients in emergency department (ED). The knowledge of characteristics symptoms and correct management may avoid misdiagnosis or mistakes with other severe conditions like pulmonary embolism, pericarditis or acute coronary disease.

Despite the importance of this entity, only fewer than 40 cases have been reported since 1957, when the condition was first described.

We have seen a couple of similar cases in our institution during a short period of time, and we suspect that these numbers doesn`t mean the real prevalence of epipericardial fat necrosis, so maybe this condition could be underdiagnosed. Instead, there isn't a study that tried to estimate an incidence of this entity.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10
• Est. completion date: July 2013
• Est. primary completion date: July 2013
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• patients with imaging criteria of EFN (defined as a round fat attenuation lesion with peripheral stranding located in the epipericardial fat)

Exclusion Criteria:

• no exclusion criteria

Study Design

Observational Model: Case-Crossover, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Epipericardial Fat Necrosis
• Fat Necrosis
• Necrosis

Intervention

Other:
• No intervention. It is a retrospective study
No intervention. It is a retrospective study

Locations

Country	Name	City	State
Brazil	Hospital Sirio Libanes	Sao paulo
Brazil	Hospital Sirio-Libanes	Sao Paulo

Sponsors (1)

Lead Sponsor	Collaborator
Hospital Sirio-Libanes

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Describe Clinical and Radiological data of epipericardial fat necrosis		18 months	Yes
Primary	Determinate the incidence of epipericardial fat necrosis		18 months	Yes
Secondary	Identify misdiagnosed cases of epipericardial fat necrosis		18 months	Yes

External Links

•   Abstract of the initial research presented at 2013 ATS conference