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Epileptic Seizure clinical trials

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NCT ID: NCT05567042 Not yet recruiting - Epileptic Seizure Clinical Trials

A Clinical Study of Epilepsy Localization and Prognosis Based on PET and Resting-state fMRI

Start date: October 2022
Phase:
Study type: Observational

1. By following up the prognosis of surgical patients, the application value of Cortex ID quantitative analysis in the localization of epilepsy foci was studied. 2. By studying the correlation between autonomic nerve function and epilepsy neural network in epilepsy patients, and analyzing the differences between different epilepsy patients, it can provide more information for judging the prognosis of epilepsy patients.

NCT ID: NCT04158531 Recruiting - Clinical trials for Epilepsy Intractable

REC2Stim as a Treatment for Refractory Epilepsy in the Primary Sensorimotor Cortex.

REC2Stim
Start date: November 4, 2019
Phase: N/A
Study type: Interventional

People with central lobe epilepsy (CLE), with seizures arising from the primary sensorimotor cortex, typically show a high rate of convulsive seizures that do not respond to anti-epileptic drugs, but have a large impact on quality of life. They often seek surgical relief, but since the area contains the body's indispensable sensorimotor representation, CLE surgery will lead to permanent functional deficits. Cortical stimulation case studies in CLE have shown seizure frequency reduction of more than 90%, but in our experience, stimuli in the central lobe can hardly be applied without interfering with motor function. The investigators propose cortical electrical stimulation therapy of a conceptually novel type. The investigators systematically determine individual stimulation settings, stimulation site and a seizure detection algorithm. In REC2Stim (Rational Extra-eloquent Closed-loop Cortical Stimulation), at the start of a seizure, a train of electric pulses is delivered to a nearby extra-eloquent area connected with the epileptogenic area within the sensorimotor cortex. Success will constitute a therapeutic modality for pharmaco-resistant patients with an epileptic focus in eloquent areas.

NCT ID: NCT03860467 Completed - Epileptic Seizure Clinical Trials

Epileptic Seizures in Intensive Care Units

Start date: December 1, 2019
Phase:
Study type: Observational

This retrospective observational cohort study is to assess and analyze clinical, electroencephalographic, laboratory, comorbidity, and treatment characteristics of Intensive care unit (ICU)-patients with epileptic seizures and to subsequently compare their characteristics with ICU-patients with status epilepticus (SE).

NCT ID: NCT03163719 Recruiting - Lactate Clinical Trials

Impact of Early Lactate Dosage Compared to CK for Diagnosis of a Suspected Seizure

Start date: November 28, 2016
Phase: N/A
Study type: Observational

Defining the origin of a seizure remains a difficult diagnosis. The presence of witness is not systematic, the clinical examination can be little contributory, and the delay recommended by the FSN is often surpassed for the realization of Creatine kinase (4h). In the event of a suspected seizure, an initial blood test with Creatine kinase and Lactates is often done on admission of the patient in other words before the 4hours delay. It seems interesting to harmonize the practices, to limit the patient wait in the emergencies for a deferred dosage of CK at 4 hours from the seizure and to identify an early biological marker. Objectives: To evaluate the value of blood CK and Lactate dosage in emergency procedures in the diagnosis of generalized seizures.

NCT ID: NCT03123302 Completed - Clinical trials for Intracranial Aneurysm

Our Anesthesia Experience During MRI Scan

Start date: February 1, 2017
Phase:
Study type: Observational

In this study we aim to investigate the relationship between our anesthesia practice and post procedure complications after MRI scanning with sedation. This is a retrospective, single center observational study. All patients undergoing MRI scan during the study period will be included.