Generic Substitution of Original Levetiracetam in Thai Epilepsy Patients

Status Completed

Clinical Trial Summary

The retrospective pre-post observational study was conducted to evaluate the real-world evidence of efficacy and tolerability of generic levetiracetam (oral tablet) which was switched from original levetiracetam (oral tablet) in patients with epilepsy at the national hospital for neurology and neurosurgery in Thailand. Epilepsy patients who received generic substitution to original levetiracetam at the same dose and had stable conditions of seizure were only included. In the period of 6 months, the investigators assessed the change of seizure frequency, the incidence of hospitalization due to breakthrough seizure, the incidence of adverse events and the incidence of composite outcomes related to dosage adjustment of antiepileptic drugs.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Epilepsy

Clinical Trial Details

NCT number	NCT04132063
Study type	Observational
Source	Mahidol University
Contact
Status	Completed
Phase
Start date	November 1, 2018
Completion date	May 30, 2019

View Details

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