Fecal Microbiota Transplantation for Epilepsy

Status Recruiting

Clinical Trial Summary

Increasing evidences showed the microbiota effects on neuropsychiatric disorders. This clinical trial aims to evaluate the efficacy and safety of fecal microbiota transplantation for epilepsy.

Clinical Trial Description

Very few literatures reported the clinical use of microbiota or bacteria for brain diseases. The most effective strategy for reconstruction of gut microbiota should be fecal microbiota transplantation (FMT). This study aims to evaluate the efficacy and safety of FMT for epilepsy. Patients were diagnosed as epilepsy by electroencephalogram (EEG) and MRI and clinical data when the study began and thent received repeated FMT with fecal from healthy donors.The antiepileptic medication regimen of patients remained unchanged after FMT. The primary outcome measure was the frequency of the seizures. Secondary outcome measure were the 50% response rate. . ;

Study Design

Related Conditions & MeSH terms

Epilepsy

Clinical Trial Details

NCT number	NCT02889627
Study type	Interventional
Source	The Second Hospital of Nanjing Medical University
Contact	Faming Zhang, MD,PhD
Phone	086-25-58509883
Email	fzhang@njmu.edu.cn
Status	Recruiting
Phase	Phase 2/Phase 3
Start date	November 2016
Completion date	December 2025

View Details

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