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Clinical Trial Summary

The Objective of this study is to compare 2-year retention rate of topiramate, levetiracetam and oxcarbazepine in a long term epilepsy treatment.


Clinical Trial Description

Primary objective The Objective of this study is to compare 2-year retention rate of topiramate, levetiracetam and oxcarbazepine in a long term epilepsy treatment.

Secondary objective The main secondary objective of this study is to evaluate confounding factors associated with retention rate of topiramate compared with other anticonvulsants.

1. Baseline characteristics

- Seizure Type

- Gender

- Age of onset

2. Treatment regimen

- Number of concomitant medication

- Type of drug combination

- Final target dose

- Titration speed

Other secondary objectives

The other secondary objectives of this study are to compare followings by each medication:

- Rate of seizure reduction (≥75%, ≥50%)

- Rate of seizure freedom ;


Study Design

Observational Model: Cohort, Time Perspective: Retrospective


Related Conditions & MeSH terms


NCT number NCT02098941
Study type Observational
Source Seoul National University Hospital
Contact Sang kun Lee, MD, PhD
Email sangkun2923@gmail.com
Status Recruiting
Phase N/A
Start date March 2014
Completion date December 2014

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