Clinical Trials Logo
  1. Home
  2. Epilepsy, Temporal Lobe
  3. NCT06422923

Effect of NRTX-1001, a Cellular Therapy Product, for the Treatment of Refractory Bilateral TLE

Epilepsy, Temporal Lobe Clinical Trial

Official title:
A Study of Inhibitory Interneurons (NRTX-1001) for the Treatment of Drug-resistant Bilateral Temporal Lobe Focal Seizures

Clinical Trial Summary

This study is designed to obtain open-label feasibility, safety, and seizure frequency data in patients with drug-resistant bilateral mesial temporal lobe epilepsy (MTLE) administered NRTX-1001.

Clinical Trial Description

This is an open-label study of the bilateral intrahippocampal administration of NRTX1001, with the primary endpoint to evaluate safety and a secondary endpoint to evaluate seizure metrics. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06422923
Study type Interventional
Source Neurona Therapeutics
Contact Holly Finefrock, BSHS
Phone 650-436-3045
Email holly@neuronatx.com
Status Not yet recruiting
Phase Phase 1
Start date July 15, 2024
Completion date July 15, 2040
View Details
See also
  Status Clinical Trial Phase
Completed NCT00001672 - Language Localization Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Epilepsy N/A
Active, not recruiting NCT04897776 - Stimulation of the Thalamus for Arousal Restoral in Temporal Lobe Epilepsy N/A
Recruiting NCT05947656 - Evaluation of the NaviFUS System in Drug Resistant Epilepsy N/A
Not yet recruiting NCT06036732 - A New Approach in Intensive Care Unit Consciousness Assessment: FIVE Score
Recruiting NCT04164056 - Hippocampal and Thalamic DBS for Bilateral Temporal Lobe Epilepsy Phase 4
Completed NCT03265925 - Brain Network Activation Analysis in Epilepsy
Enrolling by invitation NCT02151175 - Low-intensity Focused Ultrasound Pulsation (LIFUP) for Treatment of Temporal Lobe Epilepsy N/A
Recruiting NCT03478852 - Investigating Epilepsy: Screening and Evaluation
Recruiting NCT01273129 - Surgery as a Treatment for Medically Intractable Epilepsy
Not yet recruiting NCT06057233 - Innovative MRI to Localize the Epileptic Zone
Withdrawn NCT02913742 - The Utility of NIOM During LITT for Refractory MTLE N/A
Recruiting NCT04649008 - Localizing Epileptic Networks Using MRI and iEEG Early Phase 1
Completed NCT00931619 - GABA/Glutamate Balance in Temporal Lobe Epilepsy With and Without Major Depression
Recruiting NCT04717388 - Pathophysiology, Psycho-emotional and Cognitive Functioning Associated With Tinnitus N/A
Completed NCT00706160 - Language Mapping in Patients With Epilepsy
Recruiting NCT05339438 - Pre-operative Mapping of the Anterior Temporal Lobe Using Functional MRI Innovative Techniques in in Drug-resistant Epileptic Patients N/A
Not yet recruiting NCT04871555 - Structural Cartography of the Insula in Temporal Epilepsy Patients
Completed NCT04169581 - A Deep Learning Framework for Pediatric TLE Detection Using 18F-FDG-PET Imaging
Completed NCT00040326 - Early Surgical Intervention to Treat Epilepsy Phase 3
Recruiting NCT03871842 - Effects of tDCS on Depressive Symptoms of Participants With Temporal Lobe Epilepsy N/A