Epilepsy, Temporal Lobe Clinical Trial
Official title:
Quantitative MRI and GABA Spectroscopy to Localize the Epileptic Zone
The goal of EPI-CATCHER is to outline the clinical potential of multiparametric quantitative MRI (mqMRI) and of GABA-edited magnetic resonance spectroscopy (GABA-MRS), combined with machine learning tools, as imaging biomarkers to localize and delineate the EZ.
After informed consent, patient candidate to resection surgery will undergo two extra MRI sessions before surgery: one for multiparametric quantitative MRI (mqMRI) and one for GABA-edited magnetic resonance spectroscopy (GABA-MRS) In parallel, a group of healthy volunteers will also undergo the two MRI sessions described above, to collect reference data. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00001672 -
Language Localization Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Epilepsy
|
N/A | |
Active, not recruiting |
NCT04897776 -
Stimulation of the Thalamus for Arousal Restoral in Temporal Lobe Epilepsy
|
N/A | |
Recruiting |
NCT05947656 -
Evaluation of the NaviFUS System in Drug Resistant Epilepsy
|
N/A | |
Not yet recruiting |
NCT06036732 -
A New Approach in Intensive Care Unit Consciousness Assessment: FIVE Score
|
||
Recruiting |
NCT04164056 -
Hippocampal and Thalamic DBS for Bilateral Temporal Lobe Epilepsy
|
Phase 4 | |
Completed |
NCT03265925 -
Brain Network Activation Analysis in Epilepsy
|
||
Enrolling by invitation |
NCT02151175 -
Low-intensity Focused Ultrasound Pulsation (LIFUP) for Treatment of Temporal Lobe Epilepsy
|
N/A | |
Recruiting |
NCT03478852 -
Investigating Epilepsy: Screening and Evaluation
|
||
Recruiting |
NCT01273129 -
Surgery as a Treatment for Medically Intractable Epilepsy
|
||
Withdrawn |
NCT02913742 -
The Utility of NIOM During LITT for Refractory MTLE
|
N/A | |
Recruiting |
NCT04649008 -
Localizing Epileptic Networks Using MRI and iEEG
|
Early Phase 1 | |
Completed |
NCT00931619 -
GABA/Glutamate Balance in Temporal Lobe Epilepsy With and Without Major Depression
|
||
Recruiting |
NCT04717388 -
Pathophysiology, Psycho-emotional and Cognitive Functioning Associated With Tinnitus
|
N/A | |
Completed |
NCT00706160 -
Language Mapping in Patients With Epilepsy
|
||
Recruiting |
NCT05339438 -
Pre-operative Mapping of the Anterior Temporal Lobe Using Functional MRI Innovative Techniques in in Drug-resistant Epileptic Patients
|
N/A | |
Not yet recruiting |
NCT04871555 -
Structural Cartography of the Insula in Temporal Epilepsy Patients
|
||
Completed |
NCT04169581 -
A Deep Learning Framework for Pediatric TLE Detection Using 18F-FDG-PET Imaging
|
||
Completed |
NCT00040326 -
Early Surgical Intervention to Treat Epilepsy
|
Phase 3 | |
Not yet recruiting |
NCT06422923 -
Effect of NRTX-1001, a Cellular Therapy Product, for the Treatment of Refractory Bilateral TLE
|
Phase 1 | |
Recruiting |
NCT03871842 -
Effects of tDCS on Depressive Symptoms of Participants With Temporal Lobe Epilepsy
|
N/A |