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Epilepsy, Partial clinical trials

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NCT ID: NCT01457989 Completed - Epilepsy, Partial Clinical Trials

Meta-Analysis Plan for Pooled Data for Studies VRX-RET-E22-303 and VRX-RET-E22-304

Start date: August 2011
Phase: N/A
Study type: Observational

The objective of this meta-analysis is to provide data on long-term safety and efficacy following the recent positive Committee for Medicinal Products for Human Use (CHMP) opinion for retigabine using pooled data from ongoing open-label extension (OLE) Studies VRX-RET-E22-303 and VRX-RET-E22-304.

NCT ID: NCT01332539 Completed - Epilepsy, Partial Clinical Trials

An Observational Study to Assess the Burden of Drug-resistant Partial Epilepsy in Italy

Start date: May 2011
Phase: N/A
Study type: Observational

observational, non-interventional study in 120 patients with drug-resistant partial epilepsy, comprising two phases: a 3-month retrospective and a 6-month prospective. As control group, 120 patients with controlled partial epilepsy will be enrolled. The objective of the study is to describe the burden of illness in this epileptic population both in terms of costs and of quality of life. Costs and quality of life will be also compared between the two populations.

NCT ID: NCT00643500 Completed - Epilepsy, Partial Clinical Trials

Pharmacovigilance Study of Keppra. SPAIN - SKATE : Safety of Keppra as Adjunctive Therapy in Epilepsy

Start date: January 2002
Phase: Phase 4
Study type: Interventional

Patients with partial-onset seizures seen in community-based practices were to be included in this therapeutic use study - to assess the safety and tolerability of Keppra (Levetiracetam) and to confirm the favorable safety of the drug found during clinical development - to obtain further information about optimal dosing in daily clinical practice. Compared to previous registration trials, the study population corresponded more closely to that seen in daily clinical practice.

NCT ID: NCT00355082 Completed - Epilepsy, Partial Clinical Trials

Conversion To Monotherapy With Lamictal Extended Release Tablets For Treatment Of Partial Epilepsy

Start date: May 2006
Phase: Phase 3
Study type: Interventional

This study is being conducted to determine the effectiveness of a lower monotherapy dose of lamotrigine than that currently approved.

NCT ID: NCT00280059 Completed - Epilepsy, Partial Clinical Trials

Study Of The Safety And Efficacy Of Lyrica In The Treatment Of Newly Diagnosed Partial Epilepsy

Start date: August 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess whether Lyrica is a safe and effective treatment for partial epilepsy in comparison with an established treatment, Lamictal.

NCT ID: NCT00245713 Completed - Epilepsy, Partial Clinical Trials

Determine Effects of Adjunctive Levetiracetam on Sleep Architecture in Adults With Partial Onset Epilepsy.

Start date: March 2003
Phase: Phase 4
Study type: Interventional

Effect of adjunctive levetiracetam on polysomnography in adults with partial-onset epilepsy receiving a classical antiepileptic drug

NCT ID: NCT00175890 Completed - Epilepsy, Partial Clinical Trials

A Placebo-controlled Study of Levetiracetam In Children (1mo to 4yrs of Age) With Partial Onset Seizures.

Start date: October 2004
Phase: Phase 3
Study type: Interventional

To evaluate the safety and efficacy of levetiracetam used as adjunctive treatment in pediatric subjects age 1 month to less than 4 years with partial onset seizures. Subjects will be evaluated with 48 hour inpatient video electroencephalograms (a selection and an evaluation). Other neuropsychological clinical assessments will be performed during the 34 day length of the study.

NCT ID: NCT00160654 Completed - Epilepsy, Partial Clinical Trials

Open Label Safety and Efficacy Study of Levetiracetam in Patients With Epilepsy

Start date: November 24, 2003
Phase: Phase 4
Study type: Interventional

Community based study assessing safety and efficacy of levetiracetam in partial onset seizures. The optimal dose in daily clinical practice will be used.

NCT ID: NCT00160628 Completed - Epilepsy, Partial Clinical Trials

Open Label Safety and Efficacy Study of Levetiracetam in Korean Patients With Epilepsy

Start date: March 2004
Phase: Phase 3
Study type: Interventional

A Korean open-label, community-based trial assessing the efficacy and safety of levetiracetam as adjunctive therapy in partial epilepsy. Similarity with a similar study conducted in Caucasian epileptic subjects will be assessed.

NCT ID: NCT00160615 Completed - Epilepsy, Partial Clinical Trials

Follow-up Study of L059 (Levetiracetam) in Epileptic Patients With Partial Onset Seizures by Open Label Method

Start date: September 12, 2001
Phase: Phase 3
Study type: Interventional

The safety and efficacy of L059 was evaluated in patients who completed "N165 Clinical Trial of L059". They received L059 at a daily dose from 1,000 mg to 3,000 mg in addition to their standard concomitant AEDs