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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT00348257
Other study ID # LEORTC-HR-001
Secondary ID
Status Completed
Phase Phase 1/Phase 2
First received July 2, 2006
Last updated February 27, 2007
Start date July 2006
Est. completion date September 2006

Study information

Verified date February 2007
Source Leortec Medical Systems Ltd
Contact n/a
Is FDA regulated No
Health authority Israel: The Israel National Institute for Health Policy Research and Health Services Research
Study type Interventional

Clinical Trial Summary

Removal of unwanted hair is one of the most commonly sought cosmetic solutions. Traditional methods, such as shaving, depilatories, tweezing and waxing result in only temporary hair removal, and thus require extensive maintenance. Long term hair removal via electrolysis is generally unsatisfactory due to its time consuming, painful nature and the associated risk of scarring or pigmentary changes. Moreover, the efficacy of electrolysis is user dependent and is estimated to be reduction of only 15-50% of the unwanted hair3.

The more modern approach to long term hair removal involves laser and Intense Pulsed Light (IPL) treatment modalities. These technologies are based on the scientific principle of selective photothermolysis. During the treatment, the light energy is absorbed by the hair’s pigment (melanin) and transmitted through the hair shaft to the follicle. Conversion of this energy into heat causes a rise in the hair temperature, leading to destruction of the follicle and disruption of the hair growth mechanism, while leaving the skin undamaged.

Both laser and light devices have been proven successful in inducing permanent hair removal, as well as delayed hair growth, while causing minimal discomfort and complications. The light devices are based on the IPL technology, which differs from laser light in various physical aspects. The main difference is that while lasers emit light at a distinct wavelength, IPL delivers a wide range of wavelengths (400 1400 nm), thus allowing greater flexibility in aspects of body area, hair color and skin type LEORTEC LTD. has developed an innovative device that integrates the two treatment modalities: Laser and Intense Pulse Light (IPL) and in addition MLS - Multi Light Source- a combination of the two modalities. The purpose of this study is to evaluate the safety and efficacy of using Leortec 300 device for hair removal treatment.


Description:

STUDY OBJECTIVES

1. Primary Objective

- Safety

- To evaluate the safety of using LEORTEC-300 System for hair removal treatment, in different skin/hair colors and anatomical sites.

2. Secondary Objectives

- Effectiveness

- To assess the effectiveness of using the LEORTEC-300 system for hair removal treatment in different skin/hair colors and anatomical sites.

- Patient Satisfaction Immediately after the treatment patients will be asked to rate pain level which they felt during the treatment.

- Physician’s Satisfaction Physician's satisfaction from the technique, equipment and hair removal will be assessed by physician’s questionnaire.

STUDY DESIGN

This is a two-sites, prospective, controlled study to further test the safety and effectiveness of the LEORTEC-300 system in hair removal treatment.

SUBJECTS

1.Source and Number Subjects for the study will be recruited from patients within the community who have sought treatment for hair removal from the investigative physicians and meet all of the eligibility criteria listed below. There will be a total of 30 patients.


Recruitment information / eligibility

Status Completed
Enrollment 30
Est. completion date September 2006
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria:

- Healthy males/females between the ages of 18 to 70

- Subject is willing to go trough hair removal treatment.

- Subject understands the study procedure.

- Subject is willing to sign the inform consent.

- Subject must have the ability to comply with the study procedures and follow- up.

Exclusion Criteria:

- Age < 18 years or > 70 years.

- Use of medication for which 400nm to 1400nm light exposure is contraindicated

- Coagulation disorder.

- Infection / abscess / pains in treatment target area.

- Recently tanned skin.

- Photosensitivity or allergy.

- Psoriasis.

- Skin cancer.

- Diabetes.

- Pregnancy.

- Tattoo on targeted area.

- History of keloid scarring.

- Use of aspirin or antioxidants

- Eczema or dermatitis.

- Subject is suffering extreme general weakness.

- Subject objects to the study protocol.

- Physician objection.

- Known cognitive or psychiatric disorder

- Participation in any other clinical trial

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


Intervention

Device:
Hair removal by laser/IPL device


Locations

Country Name City State
Israel Elisha Hospital Haifa

Sponsors (1)

Lead Sponsor Collaborator
Leortec Medical Systems Ltd

Country where clinical trial is conducted

Israel, 

Outcome

Type Measure Description Time frame Safety issue
Primary Hair removal efficiency 1- N1/N2 (N1 - Average number of hairs after the treatment
Primary N2 - Average number of hairs before the treatment)