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A Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Gastroenteritis — ENIGMA  

Eosinophilic Gastroenteritis Clinical Trial

Official title:
A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamic Effect of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Gastroenteritis

Clinical Trial Summary

This is a Phase 2, double-blind, randomized, placebo-controlled study to assess the effects of AK002, given monthly for 4 doses. It is hypothesized that AK002 is more effective than placebo control (alternative hypothesis) in reducing the number of eosinophils per high power field (HPF) in gastric and/or duodenal biopsies before and after receiving AK002 or placebo versus no difference between AK002 and placebo control (null hypothesis).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03496571
Study type Interventional
Source Allakos Inc.
Contact
Status Completed
Phase Phase 2
Start date July 18, 2018
Completion date June 24, 2019
View Details
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