New Serological Markers for Eosinophilic Esophagitis

Status Recruiting

Clinical Trial Summary

The purpose of the study is to investigate if serological parameters such as "extracellular Serum-Tryptase (ST)" and "eosinophilic cationic protein (ECP)" are useful for the diagnosis and surveillance of the eosinophilic esophagitis (EE).

Clinical Trial Description

The eosinophilic esophagitis (EE) is chronic inflammatory and immunological disease. The diagnosis of EE is based upon large numbers of eosinophils in the esophagus on histopathologic examination (> 20 eosinophils per high powered field in at least one specimen) despite acid suppression with a Proton-Pump-Inhibitor (PPI) for at least two weeks.

There are no diagnostic serological markers for EE so far, so that the purpose of the study is to investigate serological markers which are established in other allergic diseases. ;

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01624129
Study type	Observational
Source	Technische Universität München
Contact	Monther Bajbouj, MD
Phone	+49-89-41402450
Email	monther.bajbouj@lrz.tum.de
Status	Recruiting
Phase	N/A
Start date	January 2011

View Details

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