Environmental Exposure Clinical Trial
Official title:
Determination of Half-life of the Carboxyhemoglobin Level and Utility of High Flow Nasal Cannula in Carbon Monoxide Toxicity in the Emergency Department
Verified date | November 2017 |
Source | Kocaeli University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
determination of the half-life of COHb in CO-poisoned patients with high flow nasal oxygen therapy in the ED.
Status | Completed |
Enrollment | 35 |
Est. completion date | February 6, 2018 |
Est. primary completion date | February 6, 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - The patients who are admitted to the emergency department with CO poisoning with a CoHB level of >10%. - The patients who accept to participate in the study. Exclusion Criteria: - The patients who are <18 years old. - The patients who need mechanical ventilation - The patients who are implemented oxygen more than 30 minutes before the ED admission - The patients who will be transferred to the hyperbaric oxygen center before the CoHB levels are decreased to the half. |
Country | Name | City | State |
---|---|---|---|
Turkey | Kocaeli University Medical Faculty | Kocaeli | Izmit |
Lead Sponsor | Collaborator |
---|---|
Kocaeli University |
Turkey,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Half life of COHb | Half life of COHb levels (%) under the high flow nasal oxygen therapy. Elimination rate of COHb will be determined in every 10 minutes according to venous blood gas COHb level. | between 20 and 120 minutes | |
Secondary | Adverse Events | Mucosal dryness, epistaxis and burn in the nasal cavity will be evaluated as a adverse events of high flow nasal cannula. | between 0 and 120 minutes | |
Secondary | Device Comfort | Patient comfort will be assessed according to verbal numeric rating scale by asking to patient to say a number between 0 to 10 with 0 being "high flow nasal cannula can not be tolerated" and 10 being " the most comfortable breath ever". | Between 0 and 120 minutes | |
Secondary | Flow Rate Tolerability | Flow rate tolerability will be assessed according to patient request to change in flow rate. | Between 0 and 120 minutes | |
Secondary | Flow Temperature Tolerability | Flow temperature tolerability will be assessed according to patient request to change in flow rate. | Between 0 and 120 minutes. |
Status | Clinical Trial | Phase | |
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