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Enuresis clinical trials

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NCT ID: NCT05842005 Recruiting - Clinical trials for Stress Urinary Incontinence

Mesh-Reduced Sling For Treating Stress Urinary Incontinence, Efficacy and Durability Trial

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The goal of this pilot study is to report the safety and efficacy of a suture-suspended mesh-reduced sling for treating stress urinary incontinence (SUI) in women. The main question[s] it aims to answer are: - investigate the efficacy of this mesh-reduced suture-based surgical technique for improving SUI symptoms - investigate the efficacy of this mesh-reduced suture-based surgical technique on key urethral support defects observed with 3D ultrasound Participants will consent to participate following which they will complete pre-operative assessments according to our routine clinical pathway. The participant will then undergo surgery and will be followed up to 12 months post-operatively via symptom assessment and pelvic exam.

NCT ID: NCT05828979 Recruiting - Clinical trials for Urinary Incontinence,Stress

Clinical Investigation to Assess a New Artificial Urinary Sphincter to Treat Urinary Incontinence in Women

Start date: May 2, 2023
Phase: N/A
Study type: Interventional

Prospective multicenter study designed to test the feasibility of the UroMems Artificial Urinary Sphincter in women

NCT ID: NCT05806164 Recruiting - Clinical trials for Urgency Urinary Incontinence

Beta-Agonist Versus OnabotulinumtoxinA Trial for Urgency Urinary Incontinence

BEST
Start date: June 6, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to compare treatment outcomes between an oral medication (beta agonist) versus onabotulinumtoxinA injections in women with urgency urinary incontinence (UUI). Participants will be randomly selected to receive one of the two treatments. The primary outcome measure will be at 3 months, and women will be followed for a total of 12 months. Based on patient expert input, there are 2 primary outcomes: Treatment satisfaction and urinary symptom severity.

NCT ID: NCT05773716 Recruiting - Clinical trials for Stress Urinary Incontinence

Electroacupuncture and Pelvic Floor Muscle Training for Male Stress Urinary Incontinence

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical study is to compare the effects of combined electroacupuncture with pelvic floor muscle training (PFMT) versus PFMT alone in the treatment of involuntary urine leakage following prostate removal procedure due to prostate cancer. The main question it aims to answer is that whether adding electroacupuncture to PFMT provides extra benefits in relieve urinary leakage and improves patients' quality of life. All participants will be required to perform daily PFMT for 6 weeks using uniformed standards. During the meantime, those assigned to the experimental group will additionally receive electroacupuncture three times per week for 6 weeks, while those in control group will receive sham treatment with same duration. Researchers will compare the urine leakage severity between the two groups to see if adding electroacupuncture can facilitate the recovery of symptom.

NCT ID: NCT05773378 Recruiting - Clinical trials for Urinary Incontinence

Do Intravaginal Devices Reduce Urinary Incontinence in Female Runners?

Start date: April 14, 2023
Phase: N/A
Study type: Interventional

More than one in five females experience the embarrassment and shame of urine leakage while exercising and this urinary incontinence (UI) is a substantial barrier to exercise. As many as one in three females with UI report that they limit their physical activity due to incontinence: 11.6% by not exercising at all, 11.3% by exercising less and 12.4% by changing the type of exercise they perform. It is imperative to look for alternatives to manage this condition, as it is a key reason why females abandon the very physical exercise that is necessary to maintain or improve their physical and mental health and their quality of life. While there is Grade A evidence for pelvic floor muscle training and some evidence for intravaginal pessaries to reduce symptoms of UI in general female populations, no study has evaluated the impact of conservative interventions specifically on UI experienced predominantly during running.

NCT ID: NCT05771597 Recruiting - Clinical trials for Urinary Incontinence

Home Biofeedback Therapy for Dyssynergic Defecation, Fecal Incontinence and Urinary Incontinence

Bioanatoner
Start date: March 27, 2023
Phase: N/A
Study type: Interventional

Biofeedback therapy is an effective treatment for the management of patients with dyssynergic defecation and constipation, urinary incontinence (UI), and fecal incontinence (FI). It is labor-intensive, costly, requires multiple office or hospital visits, is not easily available to the vast majority of patients in the community, and is not covered by many insurance companies. The purpose of this study is to 1. Evaluate home biofeedback therapy for patients with either constipation and dyssynergic defecation or urinary leakage or stool leakage by assessing the efficacy and safety of a wireless anorectal biofeedback device, and a cellphone app-based and voice guided home biofeedback training system 2. To compare the efficacy and safety of home biofeedback therapy system with the standard of care, office biofeedback therapy 3. To assess the cost-effectiveness of home biofeedback therapy.

NCT ID: NCT05771168 Recruiting - Clinical trials for Male Stress Urinary Incontinence

Surgery for Male Stress Urinary Incontinence

SMUI
Start date: September 29, 2022
Phase:
Study type: Observational [Patient Registry]

The purpose of this observational prospective study is to evaluate the success rate (cure plus improvement) of procedures for treatment of male stress urinary incontinence (artificial urinary sphincter or male slings) at 5 years of study follow-up and to determine other outcomes of surgical treatment for each of the devices and, to perform a prognostic factor analysis to identify clinical and surgical variables that correlate with (in)continence or revisions for each of the device subtypes. Cure is defined as urinary continence with no need for use of pads or the use of 1 light security pad; the improvement is defined as the reduction of≥ 50% of the number of pads with use of no more than two pads.

NCT ID: NCT05735522 Recruiting - Clinical trials for Urinary Incontinence

Effectiveness of Magnetic Stimulation in the Treatment of Female UUI.

Start date: November 25, 2021
Phase: N/A
Study type: Interventional

Urinary incontinence is becoming an increasingly common health, social and economic problem. The prevalence of urinary incontinence is estimated at 55% of the entire female population. Urgency urinary incontinence (UUI) is the least common subtype of urinary incontinence but has debilitating symptoms that lead to a decrease in quality of life. Ultimately, the urogynegology field does not have many successful types of treatments for this specific subtype. Extracorporeal magnetic stimulation of the pelvic floor is a type of conservative management that produces a magnetic field, which induces controlled depolarization of the nerves, resulting in pelvic muscle contraction and sacral S2-S4 roots neuromodulation. Therefore, it relieves symptoms of UUI and improves quality of life. There was no randomized, sham-controlled study published that researched the effectiveness of magnetic stimulation in the treatment of UUI that evaluated the success with subjective and objective methods, such as urodynamic studies. The aim of this study was to assess the efficacy of magnetic stimulation in the treatment of urgency urinary incontinence.

NCT ID: NCT05733052 Recruiting - Clinical trials for Urinary Incontinence

Pubourethral Ligament Plication for the Surgical Treatment of Stress Urinary Incontinence

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

To test efficacy and safety at six months of the proposed Pubourethral Plication Procedure (PPP) for cure of stress urinary incontinence - reinforcing pubourethral ligaments (PUL) with large diameter polyester sutures.

NCT ID: NCT05693103 Recruiting - Clinical trials for Urinary Incontinence, Stress Incontinence

The Effect of High-Intensity Focused Electromagnetic on Urinary Incontinence Symptoms

Start date: August 15, 2021
Phase:
Study type: Observational [Patient Registry]

This study is aimed at women's pelvic floor muscles, especially urinary incontinence caused by pelvic floor muscle relaxation or pelvic prolapse, to observe whether the use of (HIFEM) high-intensity focused magnetic energy chairs can help the pelvic floor muscles after this treatment Strengthening to improve the symptoms of urinary incontinence caused by the compression of the sacral nerve plexus caused by the downward movement of the uterus, thereby improving the social life and quality of life of the patient.