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Enteritis clinical trials

View clinical trials related to Enteritis.

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NCT ID: NCT01414517 Recruiting - Radiation Enteritis Clinical Trials

Study to Prevent Radiation Induced Damage to Bowel Using a Prebiotic Enhanced Diet.

Start date: August 2010
Phase: Phase 3
Study type: Interventional

The study will consist of pair of double-blind placebo-controlled trials of dietary supplementation with 15g/day FructoOligoSaccharide (FOS) for 7.5 weeks in patients with prostate carcinoma or 5 weeks in patients with cervical or endometrial carcinoma who are to undergo pelvic radiotherapy with intent to cure.

NCT ID: NCT01387594 Completed - Ulcerative Colitis Clinical Trials

Evaluate PF-00547659 On Cerebrospinal Fluid Lymphocytes In Volunteers With Crohn's Disease Or Ulcerative Colitis Who Failed Or Did Not Tolerate Anti-TNFs

TOSCA
Start date: May 3, 2012
Phase: Phase 1
Study type: Interventional

Study is designed to show a lack of effect on white blood cells circulating in the spinal fluid.

NCT ID: NCT01328925 Completed - Rotavirus Infection Clinical Trials

Efficacy Study of Nitazoxanide Suspension in the Treatment of Rotavirus Disease in Children

Start date: December 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effectiveness of nitazoxanide suspension compared to placebo in treating rotavirus disease in pediatric patients less than 6 years of age.

NCT ID: NCT01305109 Active, not recruiting - Clinical trials for Viral Gastroenteritis Due to Rotavirus

A Phase III Clinical Trial to Evaluate the Protective Efficacy of Three Doses of Oral Rotavirus Vaccine (ORV) 116E

ROTAVAC
Start date: March 2011
Phase: Phase 3
Study type: Interventional

The trial is a phase III randomized, double-blind, placebo-controlled trial with the primary objective of evaluating the efficacy of three doses of ORV 116E, 10^5.0 FFU, against severe rotavirus gastroenteritis, in comparison with a placebo in India.

NCT ID: NCT01212016 Terminated - Clinical trials for Eosinophilic Esophagitis

Immunopathogenesis of Food Allergy and Eosinophilic Gastrointestinal Disorders

Start date: August 30, 2010
Phase: N/A
Study type: Observational

Background: - Food allergies are characterized by abnormal immune system responses to certain foods, such as peanuts, strawberries, and shellfish. Some individuals with these allergies have immediate allergic reactions on contact with the food in question and need immediate treatment to prevent severe complications. In contrast, eosinophil-associated gastrointestinal disorders are related disorders in which white blood cells in the intestinal tract react to certain foods, causing abdominal pain, nausea, and other digestion problems. Researchers are interested in studying these conditions to better understand how the immune system responds to food allergies. Objectives: - To examine how the immune system responds to food allergens. - To examine how certain white blood cells contribute to disease in individuals with food allergies and other inflammatory diseases. Eligibility: - Individuals between 18 and 65 years of age who have a history of (a) severe allergic reaction to peanuts (and have peanut-specific antibodies), (b) allergy or inflammatory disease, or (c) eosinophil-associated gastrointestinal disorder (with at least two documented food allergies). - Healthy volunteers between 18 and 65 years of age who have no known allergies or asthma. Design: - All participants will have a screening visit and a procedure visit. The procedure visit will take place within 30 to 60 days of the screening visit, and will take 3 to 4 hours depending on the procedure(s) done. - Participants will be screened with a physical examination and medical history, and will provide blood samples for testing. Participants with peanut or other allergies will have additional tests to determine their levels of sensitivity to certain foods. Participants with eosinophil-associated gastrointestinal disorder will provide stool samples for testing. - At the procedure visit, participants with peanut allergies and participants with other allergies will provide blood samples and have leukapherisis to collect white blood cells for examination. - At the procedure visit, healthy volunteers and participants with eosinophil-associated gastrointestinal disorder will provide blood samples and have leukapherisis to collect white blood cells for examination. In addition, some but not all of these participants will have a procedure called esophagogastroduodenoscopy (EGD), which will examine the esophagus, stomach, and small intestine. Participants who are scheduled to have EGD will be asked to fast for 6 hours before the procedure.

NCT ID: NCT01113346 Recruiting - Clinical trials for Viral Gastroenteritis

A Pilot Study of Filtrum-STI in Children With Viral Gastroenteritis

F-GE-09
Start date: June 2010
Phase: Phase 2/Phase 3
Study type: Interventional

This is a phase II double blind multicenter randomized placebo-controled clinical study aimed to find out whether treatment with Filtrum-STI (orally administered 0,4g tablets) is safe and effective in children with viral gastroenteritis. Filtrum-STI (lignin hydrolytic) is a drug with a high absorbing ability, that binds and eliminates toxins, pathogenic microorganisms and viruses. Filtrum-STI is inoffensive for mucous membranes, enhances colonic propulsion and improves its natural microflora. The drug is not toxic and well combines with other medication

NCT ID: NCT01073384 Completed - Enteritis Clinical Trials

A Dose Ranging Study of Delayed Release Beclomethasone for Prevention of Acute Enteritis in Patients With Rectal Cancer

Start date: December 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and preliminary efficacy of four doses of SGX201 in subjects with rectal cancer treated with concurrent radiation and chemotherapy.

NCT ID: NCT01065324 Recruiting - Bleeding Clinical Trials

Balloon-assisted Enteroscopy and Bacteria

Start date: February 2010
Phase: N/A
Study type: Observational

1. Balloon-assisted enteroscopy (BAE) is a new tool to investigate small intestinal diseases. 2. Deep enteroscopy made possible by balloon expansion and manipulation of small intestines. 3. However, whether intestinal barrier injured during BAE predispose patients to bacteremia or clinical relevant infection is not studied. 4. We will also examine relevant patient factors.

NCT ID: NCT00828399 Completed - Clinical trials for Acute Radiation Enteritis

Prevention of Acute Radiation Enteritis With Glutamine

Start date: January 2009
Phase: Phase 4
Study type: Interventional

Ionizing radiation has cytotoxic effects, and is commonly used as treatment for neoplasm. A common adverse effect of radiation is acute diarrhoea. Glutamine is an aminoacid with antioxidant effects that can protect tissues of damage dued to radiation. The investigators designed a randomized, double-blind trial phase III to study if glutamine prevents acute radiation enteritis.

NCT ID: NCT00816842 Completed - Clinical trials for Malabsorption Syndromes

Plasma Citrulline Concentration in Tropical Enteropathy

Start date: October 1998
Phase: N/A
Study type: Observational

Citrulline is an amino acid produced in the intestine and in the liver, but the liver does not contribute significantly to circulating citrulline concentrations. The intestine is thus the only organ that normally releases significant amounts of citrulline into the blood stream. The investigators have designed a study looking at the value of measuring plasma citrulline concentration in patients with tropical enteropathy of mixed HIV status. The focus will be on the ability of the intestine to sustain the individual concerned from a nutritional standpoint. The investigators hypothesise that plasma citrulline concentration is a marker of small bowel absorptive integrity and an appropriate surrogate for HIV related enteropathy.