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Effect of Glutamine on Gastric Emptying and Length of Parenteral Nutrition in Premature Neonates

Enteral Feeding Clinical Trial

Official title:
Effect of Glutamine on Gastric Emptying and Length of Parenteral Nutrition in Premature Neonates

Clinical Trial Summary

This study investigates the effects of enterally supplied glutamine on gastric emptying, intestinal transit, age of total enteral nutrition and age at the end of hospitalisation. Forty neonates, aged at least 2 days and free of acute illness participate in a prospective, randomised, double-blind study. All are fed with parenteral and enteral nutrition enriched with glutamine (0.7 g/kg/per day, group 1) or isonitrogenous control (group 2). Gastric emptying is analysed by sequential measure of intragastric residue by diluted polyethylene glycol (PEG) 4000. Intestinal transit is analysed by Rouge Carmin test.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00213668
Study type Interventional
Source University Hospital, Rouen
Contact
Status Completed
Phase Phase 4
Start date April 2002
View Details
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