Identification of Entamoeba Spp. in Assuit Governorate Hospitals.

Entamoeba Spp. Identification Clinical Trial

Official title:

Different Methods for Detection and Identification of Entamoeba Species in Assuit Governorate Hospitals.

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04466449
• Other study ID #: Entamoeba spp. Identification
• Status: Recruiting
• Start date: September 2022
• Est. completion date: October 2022

Study information

• Verified date: February 2022
• Source: Assiut University
• Contact: Youstina Talaat
• Phone: 01225530091
• Email: youstinatalaat63[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

1. Determination the prevalence of Entamoeba histolytica infections among patients at Assiut University Hospitals presented with diarrhea/dysentery.

2. Evaluatation the role of different cultures in diagnosing Entamoeba .

3. Molecularly differentiation between Entamoeba species to monitor the true prevalence of E.histolytica .

Description:

Entamoeba histolytica is a common pathogenic protozoan widely distributed throughout the world (10% of the world's population), with 50,000-100,000 deaths reported annually(1) .It is a health problem both in Egypt and worldwide (2) The disease is more prevalent in densely populated areas with poor hygiene requirements and lacking sanitary water supply, especially in rural areas(3). It causes many digestive complications including diarrhea , and fever(2). it transmits through bloodstream forming abscesses in the brain, eye, liver and other vital organs and tissues or even lead to death in some cases . Some individuals have no symptom of the disease but transmit the infection to others(4) It is well- established that E. histolytica leads to invasive disease in humans. Although both E. dispar and E. moshkovskii are still considered to be non pathogenic and free-living amoebas, respectively, some reports suggest their potential role in provoking disease in humans (5) Cysts of E.dispar , E.moshkovskii and E.hartmanni can be confused with E.histolytica. cysts in the parasitological examination(6) The molecular assays, is preferable as it detects E. histolytica , differentiates it from other species and monitors its true prevalence for better treatment and effective control (2)

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 138
• Est. completion date: October 2022
• Est. primary completion date: September 2022
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• : Male and female patients of different age groups with diarrhea/dysentery attending the outpatient clinics at Assiut University Hospitals .

Exclusion Criteria:

• No exclusion criteria .

Related Conditions & MeSH terms

• Entamoeba Spp. Identification

Intervention

Diagnostic Test:
• stool sample
A stool sample will be collected from each patient for diagnosis of Entamoeba

Locations

Country	Name	City	State
Egypt	Youstina Talaat	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Determination the prevalence of Entamoeba histolytica infections among patients at Assiut University Hospitals presented with diarrhea/dysentery	Different Methods for Detection and Identification of Entamoeba species in Assuit Governorate.	2022