Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT02594618 |
| Other study ID # |
2014/00631 |
| Secondary ID |
|
| Status |
Completed |
| Phase |
N/A
|
| First received |
October 27, 2015 |
| Last updated |
August 1, 2016 |
| Start date |
August 2014 |
| Est. completion date |
April 2016 |
Study information
| Verified date |
August 2016 |
| Source |
Clinical Nutrition Research Centre, Singapore |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
Singapore: Domain Specific Review Boards |
| Study type |
Observational
|
Clinical Trial Summary
The aim of this study is to assess energy regulation of overfeeding and performing common
household activities in young Chinese males using whole-body room calorimetry up to 10
hours.
Description:
This study will require participants to stay in the room calorimeters for up to 5 hours on
each of the 3 test sessions. The participants are to avoid intense physical activity/alcohol
and to record their food intake for the day prior to test day. They will record their food
intake for the day prior to test session 1 in a food diary (to be provided to them on the
day of screening). Records will be used to ascertain participants' food intake patterns.
They will report to Clinical Nutrition Research Centre (CNRC) in the morning after an
overnight (10-12 hours) fast. Basic anthropometric measurements will be taken at the start
of the test session before participants enter the room calorimeter. The room calorimeter is
a 13.5 m3 chamber furnished with features to give an impression of a normal room with
windows on three sides of the chamber for outside view and visual contact with researchers.
It has a full sized foldaway bed, a fold-down writing table, an office chair, a built-in
sink and mirror, a portable freeze-dry toilet bowl, a television, a telephone, computer
network connection, an intercom system. During their stay in the room calorimeter, energy
expenditure will be measured based on recorded oxygen consumption and carbon dioxide
production over 10 hours. Participants are allowed to rest, sit and move freely, except
sleep or exercise during their stay. On each of the 3 test sessions, the subjects will
perform up to 4 common household activities (e.g. mopping floor, washing dishes, etc) 1 hour
after consuming the light breakfast. On test session 1, the light breakfast consist of
biscuits and a juice drink and will be provided to the participants after they have
undergone assessment of metabolism at rest for approximately 45 minutes in the room
calorimeter. On test session 2 and 3, the same light breakfast will be provided after
approximately 15 minutes after they have entered the room calorimeter. During their 4-5
hours stay in the room calorimeter, they will simulate a particular household activity for
up to 20 minutes and rest for 30 minutes before continuing with another household activity
and so on for up to 4 different household activities at each of the test sessions.
