Metabolomic Alterations in the Vascular Compartment in Patients With Sepsis

Endothelial Dysfunction Clinical Trial

— METSEP  

Official title:

Metabolomic Alterations in the Vascular Compartment in Patients With Sepsis - an Observational Study

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT03655899
• Other study ID #: Metabolomics 16024946
• Status: Terminated
• Start date: October 23, 2017
• Est. completion date: March 12, 2019

Study information

• Verified date: September 2019
• Source: Rigshospitalet, Denmark
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study will investigate the metabolic alterations of vascular cells caused by sepsis and septic shock

Description:

This study will investigate the metabolic alterations of vascular cells caused by sepsis and septic shock in 60 patients

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 37
• Est. completion date: March 12, 2019
• Est. primary completion date: March 12, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• 18 year or older

• Sepsis or Septic shock

Exclusion Criteria:

• Pregnant or breastfeeding

• Hemoglobin = 5.0 mmol/L

• Platelets = 5.0 mia/L

• Consent not obtainable

• Do not resuscitate order

Related Conditions & MeSH terms

• Endothelial Dysfunction
• Sepsis

Locations

Country	Name	City	State
Denmark	Bispebjerg Hospital	Copenhagen	Copenhagen NV

Sponsors (1)

Lead Sponsor	Collaborator
Pär Johansson

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Shock induced endotheliopaty	Mortality	Up to 30 days