Acute Effects of E-Cigarette Aerosol Inhalation

Status Completed

Clinical Trial Summary

This study comprises a portion of a larger study designed to compare results of vascular function in non-smokers to vascular function in healthy smokers chronically exposed to nicotinized electronic cigarette aerosol versus conventional cigarettes.

Clinical Trial Description

Here, we 1) investigate the acute effects of non-nicotinized e-cigarette aerosol inhalation in nonsmokers in terms of blood-based markers of inflammation and oxidative stress, and 2) evaluate their association with hemodynamic-metabolic MRI parameters quantifying peripheral vascular reactivity, cerebrovascular reactivity, and aortic stiffness. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03479203
Study type	Interventional
Source	University of Pennsylvania
Contact
Status	Completed
Phase	Early Phase 1
Start date	May 22, 2018
Completion date	August 31, 2022

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