Endothelial Dysfunction Clinical Trial
Official title:
Effects of Oral Supplementation With Creatine on Plasma Homocysteine Levels and Systemic Microvascular Endothelial Function in Vegetarian Individuals
Verified date | July 2017 |
Source | National Institute of Cardiology, Laranjeiras, Brazil |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The present study aims at investigating the effects of the oral supplementation with creatine on the systemic microvascular reactivity and plasma levels of homocysteine in vegetarian individuals of the vegan type.
Status | Completed |
Enrollment | 49 |
Est. completion date | June 2017 |
Est. primary completion date | June 2017 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 40 Years |
Eligibility |
Inclusion Criteria: - healthy vegetarians of the vegan type Exclusion Criteria: - previous treatment with dietary supplements - high intensity physical activity |
Country | Name | City | State |
---|---|---|---|
Brazil | National Institute of Cardiology, Ministry of Health, Brazil | Rio de Janeiro |
Lead Sponsor | Collaborator |
---|---|
National Institute of Cardiology, Laranjeiras, Brazil |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Reactivity of the systemic microcirculation | Assessment of the endothelial-dependent microvascular reactivity in the skin using laser speckle contrast imaging | three-week treatment | |
Secondary | cutaneous microvascular density | Assessment of skin microvascular density using video-capillaroscopy | three-week treatment | |
Secondary | Homocysteine levels in the plasma | three-week treatment |
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