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Endoscopic Submucosal Dissection clinical trials

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NCT ID: NCT01879904 Completed - Clinical trials for Colorectal Neoplasms

Evaluation of Endoscopic Submucosal Dissection (ESD) Efficacy

DISSECMUC
Start date: February 2010
Phase: N/A
Study type: Interventional

Superficial rectal tumors could be removed by ESD with two major advantages showed by the literature: high rate of monobloc resection and R0 resection. Hence, recurrence rate was lower than ERM therapy. This technique is actually performed routinely in Japan and experience is limited in Europe, with few data in the literature. This study is suggested to patients with superficial medium or distal rectal tumors. The lesion was identified and demarcated using white-light endoscopy, magnifying endoscopy, and chromoendoscopy. Then, marking around the lesions was performed. Local injection was made using injection needle, and then mucosal incision was performed around the lesion using endo-knives. Submucosal dissection was performed using endo-knives. Hemostasis and vessel coagulation were practiced using primary hemostatic forceps during the procedure. Follow-up is one year. For lesion with invasive carcinoma (vessel and lymphatic involvement, undifferentiated, free margin less than 1 mm), a surgical resection is performed. All the patients have an endoscopic control 3 months after ESD (rectosigmoidoscopy with biopsies): - For complete resection, an endoscopic control was performed at 1 year. - For incomplete resection, another endoscopic therapy was attempted (EMR) an endoscopic control was performed at 1 year. At one year, patient with incomplete resection have a surgical resection.

NCT ID: NCT01394861 Completed - Clinical trials for Endoscopic Submucosal Dissection

Endoscopic Submucosal Dissection (ESD)- Master Slave Robotic System - Human Study

ESD
Start date: June 2011
Phase: Phase 0
Study type: Interventional

The purpose of this study is to evaluate the feasibility, ease and safety of flexible endoscopic robotic system to treat early gastric cancer in humans.

NCT ID: NCT01132469 Recruiting - Clinical trials for Early Gastric Cancer

Efficacy and Safety Study of Endoscopic Submucosal Dissection for Early Gastric Cancer

ESD
Start date: May 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and clinical effectiveness of ESD(Endoscopic Submucosal Dissection) for early gastric cancer analyzing short-term and long-term results of endoscopic treatment.