Endophthalmitis Clinical Trial
Official title:
Concentrating on Antisepsis: 5% vs. 10% Povidone-Iodine Prior to Intravitreal Injection
This is a randomized controlled single blind prospective study evaluating the efficacy of ocular surface sterilization between three different povidone-iodine preparation techniques prior to intravitreal injection. The primary end point is significant different between median colony-forming units pre- and post-sterilization and injection.
Status | Not yet recruiting |
Enrollment | 30 |
Est. completion date | July 1, 2018 |
Est. primary completion date | April 1, 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 100 Years |
Eligibility |
Inclusion Criteria: - enrollment will be open to men and women of all ethnic backgrounds between the ages of 18-100 who are offered intravitreal injections by Dr. Anthony Mazzulla at his Retina clinic at the Ochsner Clinic Foundation as a treatment for diabetic macular edema, proliferative diabetic retinopathy, age related exudative macular degeneration, or any other cause of choroidal neovascularization or cystoid macular edema. Exclusion Criteria: - Current eye infection, actively treated blepharitis, current use of topical or systemic antimicrobial agents, current use of topical or systemic corticosteroids, allergy to iodine, pregnancy, children. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Matthew Bolton |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Median Colony-Forming Units | Median CFUs compared pre- and post-injection | 3 months | |
Secondary | Patient's ocular surface symptoms during sterilization with povidone-iodine | Survey-based | 3 months |
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