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Clinical Trial Summary

Endometriosis (EMs) is one of the most prevalent benign gynaecological diseases, and it is an inflammatory oestrogen-dependent condition. Several authors have proposed that anatomical, genetic, endocrine, immunological, environmental, hormonal, and inflammatory factors may influence tissue implantation outside the uterus. An approach to EMs aetiology that involves defining a profile to the vaginal and gut microbiota, estrogenic activity, and exposure to xenoestrogens and also metabolic and nutritional status of women with EMs may help identify some important patterns to better characterize this disease and also to define more personalized nutritional strategies, also predicting patients' predisposition to therapy success. This is an observational study on premenopausal woman, diagnosed with EMs, who will be recruited on the outpatient gynaecology appointment, to evaluate the vaginal and intestinal microbiome, measure the total estrogenic activity, assess the metabolic biomarkers and the nutritional status.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05788952
Study type Observational
Source Universidade Nova de Lisboa
Contact Diana Teixeira, PhD
Phone +351218803000
Email diana.teixeira@nms.unl.pt
Status Not yet recruiting
Phase
Start date June 1, 2023
Completion date December 1, 2024

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