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NCT04015297 Clinical Trial

Raman Spectroscopy and Endometriosis

Endometriosis Clinical Trial

Official title:
The Role of Raman Spectroscopic Analysis for Endometriosis Diagnosis

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04015297
Other study ID # ob&gyn raman
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date January 1, 2019
Est. completion date September 1, 2020

Study information
Verified date July 2019
Source Acibadem University
Contact Bahar Yuksel
Phone 05424732003
Email baharyl86@gmail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

We aimed to use Raman spectroscopy to detect differences between healthy controls and patients with surgically proven endometriosis.

Description:

Endometriosis is a chronic disease whose molecular basis is still unknown and diagnostic methods are controversial. The diagnosis is still invasive and there are no accepted ways which are molecular-based and noninvasive. Raman spectroscopy is a vibrational spectroscopy technique which can analyze specific spectral patterns, substances and molecular changes with high specificity. We aimed to use Raman spectroscopy to detect differences between healthy controls and patients with surgically proven endometriosis.

Recruitment information / eligibility
Status Recruiting
Enrollment 40
Est. completion date September 1, 2020
Est. primary completion date December 1, 2019
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 18 Years to 45 Years
Eligibility Inclusion Criteria:

- proven endometriosis

Exclusion Criteria:

- having additional health conditions

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• raman analysis
negative or pozitive

Locations
Country Name City State
Turkey Bahar Yuksel Istanbul

Sponsors (1)
Lead Sponsor Collaborator
Acibadem University

Country where clinical trial is conducted

Turkey, 

References & Publications (2)

Eberhardt K, Stiebing C, Matthäus C, Schmitt M, Popp J. Advantages and limitations of Raman spectroscopy for molecular diagnostics: an update. Expert Rev Mol Diagn. 2015 Jun;15(6):773-87. doi: 10.1586/14737159.2015.1036744. Epub 2015 Apr 15. Review. — View Citation

Lyng FM, Traynor D, Ramos IR, Bonnier F, Byrne HJ. Raman spectroscopy for screening and diagnosis of cervical cancer. Anal Bioanal Chem. 2015 Nov;407(27):8279-89. doi: 10.1007/s00216-015-8946-1. Epub 2015 Aug 16. Review. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary diagnostic specificity differentiating endometriosis patients from healthy controls by computer based technology designed with raman data 2 years
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