Endometriosis Clinical Trial
Official title:
Evaluation Des Performances de la Tomographie Par Emission de Positons Avec la 16α-[18F]Fluoro-17β-estradiol ([18F]-FES) Pour le Diagnostic de l'Endometriose
Endometriosis is a benign chronic disease responsible for infertility and pelvic pain. One of
the main problem of endometriosis is the significant delay of diagnosis.This delay has
significant consequences for patients. Currently the definitive diagnosis of endometriosis
and the evaluation of its lesional extension require performing laparoscopy and a
histological analysis of biopsy and pathologic areas. Lesions of endometriosis whose
development and growth are estrogen-dependent, express estrogen receptor (ER). [18F]FES
(16α-[18F]Fluoro-17β-estradiol) is an analog of estrogen, used in positron emission
tomography (PET), and a specific tracer of ER. We propose to evaluate the performance of this
functional imaging as a diagnostic tool for endometriosis.
The aim of this multicenter, prospective, open study is to assess sensitivity of PET with
[18F] -FES for diagnosing endometriosis compared to the gold standard (histological
confirmation on biopsy or excision of lesions performed during laparoscopy) in women care for
suspected endometriosis and for whom laparoscopy is already scheduled.
n/a
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