Endometriosis Clinical Trial
Official title:
Investigation of Cortical Plasticity in a Complex Intervention for Endometriosis
The aim of the study is to test, if patients suffering from Endometriosis show changes in
their brain function, when being treated with SART (Systemic Autoregulation Therapy), a
complex intervention consisting of interventions from Traditional Chinese Medicine (TCM) and
Western Hypnotherapy. Functional and structural brain changes are assessed using Magnetic
Resonance Imaging data which are analyzed by means of voxel-based morphometry (VBM),
connectivity and perfusion analysis. A third outcome measure are changes of patients' heart
rate variability, indicating the activity of their autonomic nervous system.
With a number of questionnaires, changes in dysmenorrhea, chronic pelvic pain, menstruation
regularity, dyspareunia, defecation pain, and quality of life are assessed during the SART
treatment.
During the treatment, we expect to see changes in cortical thickness, functional
connectivity and perfusion of pain-related areas of the cortex, that correlate with the
changes in heart rate variability.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Basic Science
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