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NCT00625950 Clinical Trial

Endometriosis Patients Undergoing Quinagolide Treatment

Endometriosis Clinical Trial

Official title:
Effect of Treatment With Agonist Dopaminergics on Endometriosic Lesions.

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00625950
Other study ID # VLC-AP-10208-208-1
Secondary ID
Status Completed
Phase Phase 4
First received February 20, 2008
Last updated January 9, 2009
Start date February 2008
Est. completion date May 2008

Study information
Verified date January 2009
Source Instituto Valenciano de Infertilidad, IVI VALENCIA
Contact n/a
Is FDA regulated No
Health authority Spain: Ethics Committee
Study type Interventional

Clinical Trial Summary

Dopamine agonists, such as quinagolide, are able to act on the VEGFR-2 blocking antibodies, diminishing Vascular Endothelial Growth Factor effect on angiogenesis in human endometriotic lesions.

Recruitment information / eligibility
Status Completed
Enrollment 5
Est. completion date May 2008
Est. primary completion date April 2008
Accepts healthy volunteers No
Gender Female
Age group 18 Years to 37 Years
Eligibility Inclusion Criteria:

- Hyperprolactinemia

- Unexplained infertility

- Endometriosis

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Health Services Research

Related Conditions & MeSH terms

Intervention

Procedure:
• ENDOMETRIAL BIOPSY
Two routine laparoscopies in period of three months with endometrial biopsy comparative study performed.

Locations
Country Name City State
Spain Instituto Valenciano de Infertilidad Valencia

Sponsors (1)
Lead Sponsor Collaborator
Instituto Valenciano de Infertilidad, IVI VALENCIA

Country where clinical trial is conducted

Spain, 

Outcome
Type Measure Description Time frame Safety issue
Primary observation of three month treatment with Quinagolida in endometriosis patients onset and three months after onset No
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