3D Printed Custom Applicators for HDR BT (DISCO)

Status Recruiting

Clinical Trial Summary

Intracavitary brachytherapy for gynaecological cancer currently use cylinder-type applicators or custom wax moulds to place a radioactive source in close proximity to the treatment area and provide highly conformal dose distributions. This study is a Phase IIa non-randomised interventional pilot trial that will investigate the feasibility of successfully treating patients with 3D-printed custom applicators.

Clinical Trial Description

Intracavitary brachytherapy for gynaecological cancer currently use cylinder-type applicators or custom wax moulds to place a radioactive source in close proximity to the treatment area and provide highly conformal dose distributions. Current workflows for designing and constructing custom applicators with wax moulds are complex, time consuming and can result in a device that fails to meet original design specifications dictated by the planning system. In contrast, 3D-printed custom applicators provide the ability to design and print patient-specific devices that match optimal design specifications. The workflow for 3D-printed applicators is also more efficient with lower turn-around time and labour/equipment costs, and ensures a more robust product for treatment. Despite these advantages there is currently no radiotherapy department offering 3D printed custom applicators at present. This study will investigate the feasibility of successfully treating gynaecological cancers with 3D-printed custom applicators. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06432478
Study type	Interventional
Source	Royal North Shore Hospital
Contact	Marita Morgia, MD
Phone	9463 1300
Email	Marita.Morgia@health.nsw.gov.au
Status	Recruiting
Phase	N/A
Start date	November 24, 2023
Completion date	September 2028

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