Endometrial Cancer Clinical Trial
— E-CTCOfficial title:
Preliminary Descriptive Exploratory Pilot Study Research of Circulating Tumor Cells Released During Endometrial Cancer Surgery
Verified date | September 2021 |
Source | University Hospital, Montpellier |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this study is to investigate the spread of Circulating Tumor Cells (CTC) during surgery in endometrial cancer. Although this cancer is often discovered at early stage, the risk of recurrence is estimated at 6 to 21%, according to grade. Early stage tumor is accessible for curative surgical treatment by laparoscopy but this kind of surgery may induce CTCs spread, and could be an explanation of this recurrence. Through this study, concordance between two blood punction sites, peripheral vein and ovarian vein, will be evaluated to detect these cells during surgery.
Status | Completed |
Enrollment | 15 |
Est. completion date | September 16, 2021 |
Est. primary completion date | September 15, 2021 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Patients with endometrial cancer - Being affiliated or benefiting from a French social security system Exclusion Criteria: - Patients with an other cancer |
Country | Name | City | State |
---|---|---|---|
France | Montpellier University Hospital | Montpellier | |
France | CHU de Nîmes | Nîmes |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Montpellier |
France,
Francini S, Duraes M, Rathat G, Macioce V, Mollevi C, Pages L, Ferrer C, Cayrefourcq L, Alix-Panabieres C. Circulating Tumor Cell Detection by Liquid Biopsy during Early-Stage Endometrial Cancer Surgery: A Pilot Study. Biomolecules. 2023 Feb 24;13(3):428. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Qualitative assessment | Presence or not of at least one CTC during endometrial cancer surgery detected on two venipuncture site (peripheral and ovarian vein). | During surgery (at the ligature of the ovarian ligament) | |
Secondary | Quantitative assessment | Number of CTC detected from each sampling | Before surgery and during surgery |
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