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NCT03824613 Clinical Trial

Urinary miRNA in Endometrial Cancer Study

Endometrial Cancer Clinical Trial

Official title:
Urinary microRNA Expression in Endometrial Cancer Patients - a Feasibility Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03824613
Other study ID # 2018.RCHT.97.
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 8, 2019
Est. completion date March 26, 2020

Study information
Verified date February 2021
Source Royal Cornwall Hospitals Trust
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study is a prospective feasibility study with the addition of a retrospective cohort study on the the expression of microRNA in urine in endometrial cancer patients.

Recruitment information / eligibility
Status Completed
Enrollment 164
Est. completion date March 26, 2020
Est. primary completion date March 26, 2020
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 18 Years and older
Eligibility Inclusion Criteria: - Confirmed diagnosis of endometrial cancer - Age: 18 years or older Exclusion Criteria: - Prior or coexisting other malignancies - Autoimmune disorders (other than diabetes mellitus)

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Urinary miRNA
MiRNA detection in urine

Locations
Country Name City State
United Kingdom Royal Cornwall Hospital Truro Cornwal

Sponsors (1)
Lead Sponsor Collaborator
Royal Cornwall Hospitals Trust

Country where clinical trial is conducted

United Kingdom, 

Outcome
Type Measure Description Time frame Safety issue
Primary Accuracy of predictive value of miRNA test in detecting endometrial cancer To determine if miRNA can distinguish endometrial cancer patients from healthy patients 6 months
Secondary Correlation to final histology To determine how well miRNA correlates with final histology, i.e. can miRNA determine the subtype of endometrial cancer 6 months
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