Endometrial Cancer Clinical Trial
Endometrial cancer is the second common gynecologic malignancy in Taiwan. The prevalence has
been overcome the epithelial ovarian cancer because of the change of life style to western
style recently. Most patients with endometrial cancer are stage I & II, the most histology
is still "endometrioid adenocarcinoma" (type I endometrial cancer). In statistics, advanced
stage (FIGO stage III and IV) is approximately 16% of all cases.
Most patients has good outcome of endometrial cancer because their surgical stage is
belonged to "early stage". However, the recurrence, distant metastases and mortality are
high if the diseases is confirmed to be advanced stage. The adjuvant therapies after
staging/debulking operation are systemic chemotherapy and whole pelvic radiation therapy/
brachytherapy. Whether the adjuvant therapy can cure the disease of not is still
controversial.
Because of the rarity of the advanced endometrial cancer, varies adjuvant therapeutic
modalities, eg. chemotherapy only, pelvic radiation therapy only, combination of
chemotherapy and radiation therapy or sequential "sandwich" therapy were ever used for such
group patients in each medical center. But the case number is insufficient and limited to
show the survival or progression free benefit during the statistics. Besides, the surgical
procedures and adjuvant therapy for early endometrial cancer is still remained to be
determined. The investigators are also interested to analyze the factors affecting their
survival.
The investigators will perform a retrospective study to review the data of patients with
endometrial cancer in Department of Obstetrics & Gynecology in Far Eastern Memorial
Hospital.
n/a
Observational Model: Case-Only, Time Perspective: Retrospective
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|---|---|---|---|
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