Retrospective Study to Evaluate the Feasibility of Ovarian Preservation in Patients With Endometrial Carcinoma

Endometrial Cancer Clinical Trial

— ECWOP  

Official title:

Study for Elevate the Feasibility of Ovarian Preservation With Endometrial Carcinoma

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01560026
• Other study ID #: VHG0500
• Status: Recruiting
• Phase: N/A
• First received: June 14, 2011
• Last updated: March 24, 2012
• Start date: August 2000
• Est. completion date: December 2012

Study information

• Verified date: March 2012
• Source: Taipei Veterans General Hospital, Taiwan
• Contact: Yi-Jen Chen, MD
• Phone: 886-2-28757566
• Email: chenyj[@]vghtpe.gov.tw
• Is FDA regulated: No
• Health authority: Taiwan: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Endometrial cancer is one of the most common female malignancies in the United States, and has increased in incidence in Taiwan in recent decades.A recent population-based analysis noted that 4% of endometrial cancers occurred in women aged 40 years or younger, furthermore it is up to 15% in Taiwan according to the data of cancer registry. The standard treatment of endometrial cancer results in surgical menopause and places patients at risk for the long-term sequelae of estrogen deprivation. The goal of this study was to determine the frequency of a coexisting ovarian malignancy and to evaluate the outcome of ovarian preservation in women with treatment for endometrial cancer.

Description:

we reviewed the cases with early stage of endometrial cancer who have primary staging surgery between January 1989 to December 2009. The enrolled patients will be divided into two group (oophorectomy vs. ovary preservation) for analysis:the outcome and recurrence type.To evaluate the outcome of ovarian preservation in women with endometrial cancer .

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 300
• Est. completion date: December 2012
• Est. primary completion date: December 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 25 Years to 70 Years

Eligibility

Inclusion Criteria:

• early stage endometrial cancer after primary surgery exclusion criteria:

• MMMT, type 2 endometrial cancer

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Endometrial Cancer
• Endometrial Neoplasms

Intervention

Procedure:
• surgery
endometrial cancer with or without oophorectomy

Locations

Country	Name	City	State
Taiwan	Taipei Veterans General Hospital	Taipei	ROC

Sponsors (1)

Lead Sponsor	Collaborator
Taipei Veterans General Hospital, Taiwan

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	from the time of diagnosis to the time of disease recurrence or last follow time	the time of diagnosis to the time of disease recurrence or last follow time	disease recurrence or last follow time, up to one year	Yes