Oral Misoprostol Before Endometrial Biopsy

Status Completed

Clinical Trial Summary

An endometrial biopsy involves a thin tube being passed through the cervix (opening of the uterus) to obtain a sample of the lining of the uterus. Sometimes there may be discomfort with this procedure especially if the cervix is not dilated or opened. Previous research has suggested that taking a drug called misoprostol may help the cervix to start to dilate or open. This study will see if misoprostol will help open the cervix for an endometrial biopsy, to lessen the discomfort and make the biopsy easier to perform.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Endometrial Biopsy

Clinical Trial Details

NCT number	NCT00200226
Study type	Interventional
Source	Memorial University of Newfoundland
Contact
Status	Completed
Phase	Phase 3
Start date	February 2003
Completion date	September 2007

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See also
Status	Clinical Trial	Phase
Completed	`NCT01908738` - Effectiveness of Paracervical Block Versus Lidocaine Spray During Endometrial Biopsy	N/A
Withdrawn	`NCT00953641` - Vaginal Misoprostol for Cervical Ripening Prior to Endometrial Biopsy	Phase 3
Completed	`NCT02465320` - COL-1077 (Lidocaine Bioadhesive Gel, 10%) in Women Undergoing Transvaginal Pipelle-Directed Endometrial Biopsy	Phase 2
Recruiting	`NCT01963819` - Therapeutic Endometrial Biopsy	N/A
Not yet recruiting	`NCT06180317` - The Effect of Virtual Reality on Anxiety and Pain During Endometrial Biopsy	N/A