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Endarterectomy, Carotid clinical trials

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NCT ID: NCT02808754 Completed - Carotid Stenosis Clinical Trials

Remote Ischemic Preconditioning for Carotid Endarterectomy

RIP-CEA
Start date: December 2016
Phase: N/A
Study type: Interventional

This is a randomized controlled trial designed to test an intervention (Remote ischemic preconditioning) in patients undergoing carotid endarterectomy (CEA) for carotid artery stenosis (CAS). The outcomes of interest include neurocognitive function, cardiac complications, and biomarkers of brain ischemia.

NCT ID: NCT00710437 Completed - Clinical trials for Endarterectomy, Carotid

Effects of Dexmedetomidine on the Intraoperative Electroencephalogram During Endarterectomy Surgery

Start date: April 2005
Phase: N/A
Study type: Observational

During elective carotid endarterectomy surgery, dexmedetomidine, an FDA approved medication, is now given as part of our standard anesthetic regimen based upon its reported ability to decrease anesthetic requirements and improve the peri-operative hemodynamic profile without compromising the EEG monitoring that is used during these procedures. Although this is consistent with our clinical impression, the effects of dexmedetomidine on the perioperative course and EEG monitoring have not been objectively evaluated at our institution.

NCT ID: NCT00294606 Recruiting - Clinical trials for Echocardiography, Transesophageal

Comparison of the Effects of Phenylephrine and Norepinephrine on Cardiac Function During Carotid Artery Surgery

Start date: February 2006
Phase: N/A
Study type: Interventional

This will be a prospective, randomized, double-blinded, cross-over clinical trial to compare the effects of phenylephrine or norepinephrine on cardiac function during carotid artery surgery in patients under general anesthesia. The effect of the vasopressor on cardiac function will be measured using electrocardiography, transesophageal echocardiography and cardiac troponin I intraoperatively and postoperatively. We will use a cross-over pattern since both drugs exhibit rapid onset and short duration of action. We hypothesize that there will be less myocardial ischemia associated with the use of norepinephrine when compared with phenylephrine during carotid artery surgery.

NCT ID: NCT00288899 Completed - Surgery Clinical Trials

Benefits of 'Repeat Back' Protocols Within A Computer-Based Informed Consent Program

Start date: August 7, 2006
Phase: Phase 1
Study type: Interventional

This is a VA Merit Review Study involving 7 VA medical centers participating in a parallel group randomized trial comparing "repeat back" versus standard electronic consent for 4 common elective surgical procedures (total hip arthroplasty, carotid endarterectomy, laparoscopic cholecystectomy, and radical prostatectomy). Baseline covariates include health status (SF-12), reading ability (REALM), and demographics. Primary outcomes are patient comprehension of the informed consent, patient satisfaction with the informed consent and decision making processes, patient satisfaction with care, anxiety (STAI), and provider assessment of the "repeat back" process. In addition, we are electronically capturing data detailing time spent in each phase of the consent process including "repeat back".