Disparities Among Liver Transplant Patients

End Stage Liver DIsease Clinical Trial

Official title:

Individual and Structural-level Determinants Associated With Disparities Among Liver Transplant Patients

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05981196
• Other study ID #: 22-008581
• Status: Recruiting
• Start date: November 15, 2023
• Est. completion date: December 2024

Study information

• Verified date: November 2023
• Source: Mayo Clinic
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to inform healthcare interventions to reduce the disparities in liver transplant listing and in transplantation.

Description:

Aim 1. Establish a longitudinal cohort of patients with end-stage liver dysfunction.

Aim 2. Examine interpersonal and structural factors associated with liver transplant evaluation and listing by patient characteristics (e.g., race, ethnicity, SES, gender).

Aim 3. Examine the use of stigmatizing language among patients undergoing liver transplant based on their demographic characteristics (e.g., race, ethnicity, SES, gender).

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: December 2024
• Est. primary completion date: December 2024
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Patients with end-stage liver, kidney, or cardiac dysfunction.

Exclusion Criteria:

• Patients with more than one system with end stage organ dysfunction, dementia, cognitive or sensory impairment, prior solid organ transplant.

• Patients with potential medical exclusions for transplant.

Related Conditions & MeSH terms

• End Stage Liver DIsease
• Liver Diseases

Locations

Country	Name	City	State
United States	Mayo Clinic Arizona	Phoenix	Arizona

Sponsors (1)

Lead Sponsor	Collaborator
Mayo Clinic

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Mortality	Total number of subject deaths	Approximately one year post-transplant, or until you are removed from the transplant list
Other	Hospital length of stay	Total number of days subjects were admitted to the hospital	Approximately one year post-transplant, or until you are removed from the transplant list
Other	ICU length of stay	Total number of days subjects were admitted to Intensive Care Unit (ICU)	Approximately one year post-transplant, or until you are removed from the transplant list
Other	30-day readmission	Number of subjects to experience a 30-day readmission	Approximately one year post-transplant, or until you are removed from the transplant list
Primary	Liver transplant waiting list	Number of subjects listed on the liver transplant waiting list	Approximately one year
Primary	Organ transplantation	Number of subject to receive an organ transplantation	Approximately one year
Secondary	Survival	Total number of subject alive	Approximately one year post-transplant, or until you are removed from the transplant list
Secondary	Graft survival at six months	Total number of subject to have a functioning graft at six months post transplant	Six months post transplant
Secondary	Graft survival at one year	Total number of subject to have a functioning graft at one year post transplant	One year post transplant

External Links

•   Mayo Clinic Clinical Trials