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Sarcopenia and Physical Performance in Hemodialysis Patients

End Stage Kidney Disease Clinical Trial

Official title:
Assessment of Sarcopenia, Physical Performance and Cognitive Function in Hemodialysis Patients

Clinical Trial Summary

Many systems such as the cardiovascular, pulmonary, musculoskeletal, hematological, immunological, gastrointestinal, central nervous system are affected due to decreased kidney function. The aim of this study was to investigate the relationship between physical performance and sarcopenia, peripheral muscle strength, activities of daily living, cognitive functions, physical activity level, fragility, pain in hemodialysis patients.

Clinical Trial Description

A high prevalence of sarcopenia has been reported in end stage kidney disease. The incidence of sarcopenia increases with age. Muscle atrophy is caused by an imbalance between the anabolic and catabolic processes in chronic kidney disease. Sarcopenia and physical inactivity progress synergistically. Decreased physical performance is associated with sarcopenia. In hemodialysis patients, daily physical activity level and physical performance decrease. Cognitive impairment is common in chronic kidney disease. Uremic toxins can cause a decrease in cognitive function. One of the most important problems associated with hemodialysis is pain and pain negatively affects functional capacity and quality of life. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04669184
Study type Observational
Source Hacettepe University
Contact Merve Firat
Phone +903123051576
Email mervefirat@hacettepe.edu.tr
Status Not yet recruiting
Phase
Start date January 1, 2021
Completion date March 1, 2022
View Details
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