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End-organ Damage clinical trials

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NCT ID: NCT02684487 Withdrawn - Sepsis Clinical Trials

Vitamin D Status in Patients With Severe Sepsis

ViDISS
Start date: December 2017
Phase: Phase 3
Study type: Interventional

Sepsis is a clinical entity that complicates infection. Without early recognition and timely management, it can rapidly progress to severe sepsis, septic shock, and culminate in multiple organ dysfunction syndrome. Forty to 70% of septic patients have low vitamin D status, yet little is known about the impact of vitamin D3 (vitD3) supplementation in this patient population. As such, the investigators propose a randomized, double-blinded, placebo-controlled trial to test the hypothesis that early, rapid correction of low vitamin D status, as an adjunct to established treatment guidelines, will improve clinical outcomes and measurably alter immune profile in patients with severe sepsis.

NCT ID: NCT01872039 Completed - Clinical trials for Hypertension Emergency

Post Marketing Study to Evaluate the Two Dose Regimens of Nicardipine Injection in Hypertensive Emergency Patients

Start date: March 2013
Phase: Phase 4
Study type: Interventional

To compare the efficacy and safety of two dose adjustment regimens (i.e. weight-based and non-weight-based) for the treatment of Chinese hypertensive emergency patients.