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Clinical Feature and Microbiology Characteristics of Empyema in Children

Empyema Clinical Trial

Official title:
A Multicenter Observational Study About the Clinical Feature and Microbiology Characteristics of Empyema in Children

Clinical Trial Summary

The study is designed to clarify the clinical characteristics and reversion of children with empyema, observe the effect of streptococcus vaccine application on serotype of streptococcus, and to explore the susceptibility factors of streptococcus empyema in children in China.

Clinical Trial Description

Empyema is a major complication of bacterial community-acquired pneumonia in children. And studies have shown that although the incidence of community-acquired pneumonia in children has decreased with the application of pneumococcal conjugate vaccine, the incidence of empyema has increased, which raises the difficulty to disease treatment, and aggravates the financial burden on medical care. Streptococcus is one of the most common pathogens causing children's empyema. In recent years, although more and more researches are reported on children's community- acquired pneumonia or pleural effusion, the clinical studies on streptococcus pneumoniae empyema are rarely mentioned. Therefore, a multicenter observational study is needed to better understand the clinical characteristics and reversion of children with empyema, observe the effect of streptococcus vaccine application on serotype of streptococcus, and explore the susceptibility factors of streptococcus empyema in children in China. The study mentioned above will contribute to optimize the treatment strategy of streptococcus empyema for the future, and reduce the incidence of children's empyema. The trial will be completed in 3 years with 100 participants taken from hospitals in partnership with clinical research collaboration of National Clinical Research Center for Respiratory Diseases, China. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04695275
Study type Observational
Source Beijing Children's Hospital
Contact
Status Not yet recruiting
Phase
Start date January 6, 2021
Completion date November 30, 2022
View Details
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