Uniportal VATS Versus Chest Tube for Early Empyema

Status Completed

Clinical Trial Summary

This randomized controlled study compared uniportal video-assisted thoracoscopic surgery (U-VATS) versus chest tube drainage for initial (first-line) treatment of stage I (exudative) and stage II (fibrinopurulent) empyema in adult patients (>18 years old). The primary end-point of outcome was the overall success of treatment (no need for re-intervention or death). The main results demonstrated the safety of minimally invasive U-VATS procedure in the initial treatment of early stages of pleural empyema in comparison to traditional chest tube drainage. Initial use of U-VATS was safe and feasible due to postoperative freedom from complex or marked effusion, in addition to significant reduction in the need for additional intervention, postoperative complications, length of hospital stay, and total cost.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06325904
Study type	Interventional
Source	Minia University
Contact
Status	Completed
Phase	N/A
Start date	March 1, 2021
Completion date	December 1, 2023

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05546762` - Trial of Antiseptic Irrigation for Pleural Infection	Phase 2
Completed	`NCT04477980` - Retrospective Review on Patients With Culture Negative Empyema
Completed	`NCT05204537` - The Role of Surgery in Patients With Coronavirus Disease - 19 (COVID-19) Related Thoracic Complications
Completed	`NCT03583931` - Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication	N/A
Completed	`NCT02958683` - Chest Wall Motion Analysis in Disease
Recruiting	`NCT02165891` - Comparison of Intrapleural Urokinase and Video-Assisted Thorascopic Surgery in the Treatment of Parapneumonic Pleural Effusion in Children	Phase 3
Completed	`NCT01246453` - Efficacy and Security of Intrapleurally Alteplase vs Urokinase for the Treatment of Complicated Parapneumonic Effusion and Empyema	Phase 4
Recruiting	`NCT03584113` - VATS Decortication Versus IR Guided Chest Tube Insertion With Fibrinolytics for the Management of Empyema	N/A
Completed	`NCT03873766` - Management of Pleural Space Infections	Phase 4