Clinical Trials Logo

Clinical Trial Summary

The aim of the present study is to examine whether the neuropeptide oxytocin (OXT) influences social reward processing and whether the effects are context- and sex-dependent.


Clinical Trial Description

In a double-blind, randomized, placebo-controlled, between-subject design healthy volunteers will receive either oxytocin or placebo nasal spray (40IU in 10 puffs).

Subjects will come to the experiment in pairs (two friends of the same sex). 45 min after drug administration, the two subjects will simultaneously undergo a social reward task - during the task, functional magnetic resonance imaging (fMRI) data will be acquired from one of them. During the social reward task subjects will be asked to rate the valence and arousal of emotional pictures in three different conditions: alone, share with a stranger and share with their friend.

Before treatment, subjects will complete a range of validated questionnaires to control for potential confounders, such as level of depression (assessed using the BDI) and to explore associations between relevant personality factors and treatment effects, such as adult attachment style (assessed using the AAS). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03085628
Study type Interventional
Source University of Electronic Science and Technology of China
Contact Keith Kendrick, Dr
Email kkendrick@uestc.edu.cn
Status Recruiting
Phase N/A
Start date July 2016
Completion date December 2018

See also
  Status Clinical Trial Phase
Completed NCT05130944 - Feasibility of Community Psychosocial Intervention for Women N/A
Recruiting NCT06079853 - Nurse Suicide: Physiologic Sleep Health Promotion Trial N/A
Completed NCT05490979 - The Impact of Dyad Exercises on Well-being and Connection in Young Adults N/A
Not yet recruiting NCT05963893 - Promoting a Healthy Life Through Gender Equity
Completed NCT03849924 - Enhancing One's Sense of Self Using Self-Affirmation N/A
Active, not recruiting NCT05541653 - The IGNITE Study on Concentrated Investment in Black Neighborhoods N/A
Completed NCT03303326 - Arab American Women's Health Study N/A
Not yet recruiting NCT05542537 - Nurturing Healthy Teachers N/A
Completed NCT02785471 - Assessing Online Interventions for Men's' Mental Health and Wellbeing N/A
Completed NCT02683811 - Effectiveness of the Updated Version of the School-based Program Diario Della Salute (DDS-2) N/A
Withdrawn NCT05605028 - A Mental Health Intervention for a Community Program Called the PowerObesity N/A
Not yet recruiting NCT04537676 - Patient Empowerment Study
Recruiting NCT06324318 - Parenting in 2 Worlds Multisite Trial Phase 2
Completed NCT05455905 - Voice Biomarkers Predictive of Depression and Anxiety
Completed NCT03368014 - "Fun.Feel.Share" Lyrics-writing and Singing Show N/A
Completed NCT05109923 - Onnit Labs New Mood Supplementation in Healthy College Students N/A
Not yet recruiting NCT05825040 - Randomized Controlled Trial on Precision Mental Health N/A
Not yet recruiting NCT06023342 - Examining Engagement Predictors of Health and Fitness App Uptake and Subscription in the General Population
Completed NCT06044363 - Satir Model for Self-esteem, Mental Health, and Family Function Among Individuals With Substance Use Disorders N/A
Recruiting NCT04790162 - Heartfulness Meditation to Improve Resilience Among Health Care Students: A 90 Day Program N/A