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Comparison of Olanzapine and Metoclopramide For Treatment Of bReakThrough Emesis — COMFORT  

Emesis Clinical Trial

Official title:
Efficacy of Olanzapine in Break-through Emesis After Prophylaxis With Dexamethasone, 5-HT3 Receptor Antagonists and Aprepitant Compared to Metoclopramide

Clinical Trial Summary

This trial is designed to evaluate olanzapine compared to the metoclopramide in the treatment of break through emesis after prophylaxis with dexamethasone, 5-HT 3 receptor antagonists and aprepitant in patients receiving chemotherapy. Efficacy will be assessed using a modified MASCC questionaire with a visual analog scale.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01148264
Study type Interventional
Source Martin-Luther-Universität Halle-Wittenberg
Contact
Status Terminated
Phase Phase 2
Start date July 2010
Completion date October 2014
View Details
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