Out-Of-Hospital Cardiac Arrest Clinical Trial
Official title:
Which Patients With a ROSC After OHCA Would Potentially Benefit From Physician Driven Post Cardiac Arrest Care?
Rational: Out of hospital cardiac arrest is a devastating event with a high mortality.
Survival rates have increased over the last years, with the availability of AED's and public
BLS. Previous studies have shown that deranged physiology after return of spontaneous
circulation (ROSC) is associated with a worse neurological outcome. Good quality post-arrest
care is therefore of utmost importance.
Objective: To determine how often prehospital crews (with their given skills set) encounter
problems meeting optimal post-ROSC targets in patients suffering from OHCA, and to
investigate if this can be predicted based on patient-, provider- or treatment factors.
Study design: Prospective cohort study of all patients attended by the EMS services with an
OHCA who regain ROSC and are transported to a single university hospital, in order to
identify those patients with a ROSC after a non-traumatic OHCA who had deranged physiology
and/or complications from OHCA EMS personnel was unable to prevent/deal with in the
prehospital environment.
Study population: Patients, >18 years, transported by the EMS services to the ED of the
University Hospital Groningen (UMCG) with a ROSC after OHCA in a 1 year period
Main study parameters/endpoints: Primary endpoint of our study is the percentage of OHCA
patients with a prehospital ROSC who arrive in hospital with either a deranged physiology or
with complications from OHCA EMS personnel was unable to deal with.
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