Clinical Trial Details
— Status: Completed
Administrative data
NCT number |
NCT04478045 |
Other study ID # |
202005121RINB |
Secondary ID |
|
Status |
Completed |
Phase |
|
First received |
|
Last updated |
|
Start date |
August 1, 2020 |
Est. completion date |
July 31, 2022 |
Study information
Verified date |
August 2021 |
Source |
National Taiwan University Hospital |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Observational
|
Clinical Trial Summary
For the emergency physicians and critical care specialists, how to quickly recognize shock
from diverse clinical features and immediately treat shock patients to prevent progression to
irreversible organ dysfunction from initially reversible shock condition are important issues
and challenges. In recent years, ultrasonography had been extensively used in clinical
practice recently, and well-trained medical staffs can quickly and easily apply ultrasound to
evaluate, examine, diagnose, and even treat the patients. The clinical application of
point-of-care ultrasound can help the first-line physicians rapidly evaluate and diagnose the
main symptoms and signs of the patients at bedside, and further initially stabilize and
appropriately treat the patients subsequently. The aim of this program is to prospectively
collection of the findings of point-of-care ultrasonography in shock patients at emergency
room in NTUH. The clinical manifestations, and followed up the examinations, treatments, and
prognosis will also be collected. The effect of bedside ultrasound on differential diagnosis
and treatment of shock patients will be analyzed. The results of the current study can
provide the base for further clinical trials and set up of shock team.
Description:
Shock is defined as cellular and tissue hypoxia due to either reduced oxygen delivery,
increased oxygen consumption, inadequate oxygen utilization, or a combination of these
processes. According to the etiology about how it causes a decrease in blood flow to the
cells and tissue, there are four types of shock naming cardiogenic shock, hypovolemic shock,
obstructive shock, and distributive shock, respectively. The evaluation and management of
shock patients is an extremely difficult challenge for the emergency physicians and critical
care specialists. How to diagnose, classify, stabilize, and treat the shock patients quickly
and in time are the arduous tasks. For the emergency physicians and critical care
specialists, how to quickly recognize shock from diverse clinical features and immediately
treat shock patients to prevent progression to irreversible organ dysfunction from initially
reversible shock condition are important issues and challenges. In recent years, ultrasound
instruments have gradually developed with higher radiographic quality and lower cost.
Ultrasonography had been extensively used in clinical practice recently, and well-trained
medical staffs can quickly and easily apply ultrasound to evaluate, examine, diagnose, and
even treat the patients. The clinical application of point-of-care ultrasound can help the
firstline physicians rapidly evaluate and diagnose the main symptoms and signs of the
patients at bedside, and further initially stabilize and appropriately treat the patients
subsequently. The aim of this program is to prospectively collection of the findings of
point-of-care ultrasonography in shock patients at emergency room in NTUH. The clinical
manifestations, and followed up the examinations, treatments, and prognosis will also be
collected. The effect of bedside ultrasound on differential diagnosis and treatment of shock
patients will be analyzed. The results of the current study can provide the base for further
clinical trials and set up of shock team.