Emergencies Clinical Trial
Official title:
Population Pharmacokinetics of Metronidazole in Neonates: Evaluation and Optimization of the Dose
The objective of NEOPOPI is to conduct a population pharmacokinetic study of metronidazole in
neonates, in order to evaluate and optimize neonatal dose regimen.
There will be no change to the medication treatment received by participants. An
opportunistic pharmacokinetic sampling approach will be followed: samples will be scavenged
from blood or cerebrospinal fluid drawn for routine biochemical tests. In this way, no
additional invasive tests will be needed.
- Administration of the antibiotic according to the usual procedures for prescribing
services: in particular, neither the indications nor the doses nor the methods of
administration are fixed by the protocol
- Opportunistic sampling strategy: no biological samples are specifically collected for
the purposes of the study (measurements of concentrations on "bottoms" or "left-over"
samples); the performance of this non-invasive sampling strategy has been previously
demonstrated in the neonatal population.
- Micro-analytical method (assay of concentrations on micro-volumes, of the order of 50μL)
- Population pharmacokinetic analysis
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05552989 -
Towards Better Preparedness for Future Catastrophes - Local Lessons-learned From COVID-19
|
||
| Not yet recruiting |
NCT04915690 -
Investigation on the Practice Status of Emergency Stuff
|
||
| Not yet recruiting |
NCT03424096 -
Primary Palliative Care Education, Training, and Technical Support for Emergency Medicine
|
N/A | |
| Completed |
NCT02534324 -
The Effect of Pre-discharge Blood Pressure of Patients With Asymptomatic Severe Hypertension in Emergency Department
|
N/A | |
| Completed |
NCT00991471 -
The Effect of an Physician-Nurse Supplementary Triage Assistance Team on Emergency Department Patient Wait Times
|
N/A | |
| Recruiting |
NCT03257319 -
Inhaled vs IV Opioid Dosing for the Initial Treatment of Severe Acute Pain in the Emergency Department
|
Phase 3 | |
| Recruiting |
NCT05005117 -
Laparoscopic Approach for Emergency Colon Resection
|
N/A | |
| Recruiting |
NCT03917368 -
Ultrasound Evaluation of the Jugular Venous Pulse (US-JVP)
|
N/A | |
| Completed |
NCT04601922 -
Qualitative Study of Long Term Cardiovascular Risk Prediction in the Emergency Department
|
||
| Recruiting |
NCT05497830 -
Machine Learning for Risk Stratification in the Emergency Department (MARS-ED)
|
N/A | |
| Active, not recruiting |
NCT06220916 -
The Greek Acute Dance Injuries Registry
|
||
| Recruiting |
NCT05496114 -
Medical Checklists in the Emergency Department
|
N/A | |
| Recruiting |
NCT05543772 -
Evaluation of Blood Sampling From a Pre-existed Peripheral Intravenous Catheter Line
|
Phase 4 | |
| Recruiting |
NCT06072534 -
Evaluation of Effectiveness of Two Different Doses of Mivacurium in Rapid Sequence Intubation
|
N/A | |
| Not yet recruiting |
NCT05528211 -
Safety and Efficacy of Emergent TAVI in Patients With Severe AS
|
||
| Completed |
NCT05818215 -
Impact of the Qatar 2022 FIFA World Cup on PED Use and Misuse Patterns
|
||
| Recruiting |
NCT04615065 -
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
|
||
| Active, not recruiting |
NCT04648449 -
Artificial Intelligence (AI) Support in Medical Emergency Calls
|
||
| Active, not recruiting |
NCT05221697 -
Effect of an ML Electronic Alert Management System to Reduce the Use of ED Visits and Hospitalizations
|
N/A | |
| Not yet recruiting |
NCT04431986 -
ER2 Frailty Levels and Incident Adverse Health Events in Older Community Dwellers
|