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Sevoflurane and Intravenous Anesthesia in Hypospadias Repair

Emergence Delirium Clinical Trial

Official title:
Emergence Delirium in Pediatric Age Group: Comparison Between Sevoflurane and Intravenous Anesthesia in Hypospadias Repair: A Randomized Clinical Trial

Clinical Trial Summary

Emergence agitation (EA), a phenomenon observed at the time of recovery from general anesthesia (GA).The cause of ED appears to be multifactorial in origin. Use of volatile anesthetics, prolonged duration and type of surgery, pain, and rapid emergence are some factors known to increase its incidence

Clinical Trial Description

The pathogenesis of postoperative EA is still undefined, but sevoflurane has intrinsic effects that may share in emergence agitation like its different electroencephalogram pattern from halothane, and its degradation to inorganic fluoride ions and compound A which may have a role in the occurrence of EA Sevoflurane now is the inhalational anaesthetic agent of choice for pediatrics, as it is non-pungent, with minimal airway irritation characters, and its cardiac adverse effects are minimal like cardiac depression and dysrhythmias. Total intravenous anesthesia (TIVA) using propofol and fentanyl appears to have a smooth recovery profile ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06396468
Study type Interventional
Source Benha University
Contact Ramy Saleh, MD
Phone 01024020922
Email ramymousa455@gmail.com
Status Recruiting
Phase N/A
Start date March 1, 2024
Completion date July 26, 2024
View Details
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